Abstract: The present invention discloses a process for the production of androsta-4,9(11)-diene-3,17-dione type compounds from 9.alpha.-hydroxyandrostenedione type compounds by non-aromatic oxygenated strong acid dehydration.

Abstract: This invention relates to a process whereby sterols from various sources are prepared for subsequent fermentation by dissolving the sterols in an organic diluent with subsequent removal of the organic diluent producing high substrate concentrations for fermentation.

Abstract: The present invention discloses amides and thioamides substituted in the .alpha. or .beta. position with substituted pyrazoles which are useful as herbicides.

Abstract: The present invention discloses amides and thioamides substituted in the .alpha. or .beta. position with substituted pyrazoles which are useful as herbicides.

Abstract: The present invention discloses amides and thioamides substituted in the .alpha. or .beta. position with substituted pyrazoles which are useful as herbicides.

Abstract: The present invention discloses amides and thioamides substituted in the .alpha. or .beta. position with substituted pyrazoles which are useful as herbicides.

Abstract: The present invention discloses amides and thioamides substituted in the .alpha. or .beta. position with substituted pyrazoles which are useful as herbicides.

Abstract: The present invention discloses a process for the production of -androsta-4,9(11)-diene-3,17-dione-type compounds from 9.alpha.-hydroxyandrostenedione-type compounds by forming a sulfinate ester at C.sub.9 followed by desulfination.

Abstract: The present invention discloses amides and thioamides substituted in the .alpha. or .beta. position with substituted pyrazoles which are useful as herbicides.

Abstract: This invention discloses an improved biotransformation process for the introduction of a double bond between carbon atoms 1 and 2 in corticoids by Septomyxa without degradation of the corticoid side chain.

Abstract: The present invention discloses topical preparations containing anti-inflammatory steroids. These may be ointments or solutions which contain as a solubilizing agent for the steroid, polyoxypropylene 15 stearyl ether.

Abstract: The present invention discloses amides and thioamides substituted in the .alpha. or .beta. position with substituted pyrazoles which are useful as herbicides.

Abstract: The present invention is a chemical method for obtaining an optically pure 2-aminonitrile or a 2-aminoamide from (1) an optically impure mixture, (2) a racemic mixture, or (3) the optically pure enantiomer of the opposite configuration, in an amount greater than actually present, by use of optically active acids with a ketone or an aldehyde catalyst. Yields of greater than 70 percent of one enantiomer are obtained from racemic mixtures in very short time periods.

Abstract: Substituted esters of PGA.sub.2, 15-alkyl-PGA.sub.2, and 15(R)-15-alkyl-PGA.sub.2, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes as PGA.sub.2, 15-alkyl-PGA.sub.2, and 15(R)-15-alkyl-PGA.sub.2, and are also useful as a means for obtaining highly purified PGA.sub.2, 15-alkyl-PGA.sub.2, and 15(R)-15-alkyl-PGA.sub.2 products.

Abstract: This invention discloses a general process for the production of corticoids from androstenes. This invention provides an economically viable alternative synthesis of 17.alpha.-hydroxyprogesterones and the corticoids.

Abstract: Disclosed is an anti-inflammatory compound, 6.alpha.,9.alpha.-di-fluoro-11.beta.,17.alpha.,21-trihydroxy-16.beta.-meth ylpregna-1,4-diene-3,20-dione 17,21-diacetate, and topical pharmaceutical formulations which include antimicrobial agents.

Abstract: Substituted phenyl and naphthyl esters of PGE.sub.2 analogs, including the 16-alkyl, 16-fluoro, 16-phenoxy, and phenyl-substituted analogs, and their 15-epimers, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes as these PGE.sub.2 analogs, and are also useful as a means for obtaining highly purified 16,16-dimethyl-PGE.sub.2, 16-phenoxy-17,18,19,20-tetranor-PGE.sub.2, and 17-phenyl-18,19,20-trinor-PGE.sub.2.

Abstract: Substituted phenyl and naphthyl esters of PGE.sub.2 analogs, including the 16-alkyl, 16-fluoro, 16-phenoxy, and phenyl-substituted analogs, and their 15-epimers, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes as these PGE.sub.2 analogs, and are also useful as a means for obtaining highly purified 16,16-dimethyl-PGE.sub.2, 16-phenoxy-17,18,19,20-tetranor-PGE.sub.2, and 17-phenyl-18,19,20-trinor-PGE.sub.2.

Abstract: Substituted phenyl and naphthyl esters of PGE.sub.2 analogs, including the 16-alkyl, 16-fluoro, 16-phenoxy, and phenyl-substituted analogs, and their 15-epimers, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes as these PGE.sub.2 analogs, and are also useful as a means for obtaining highly purified 16,16-dimethyl-PGE.sub.2, 16-phenoxy-17,18,19,20-tetranor-PGE.sub.2, and 17-phenyl-18,19,20-trinor-PGE.sub.2.

Abstract: Compounds of the formula: ##STR1## are disclosed, wherein R.sub.1 taken independently is hydrogen; R.sub.2 taken independently is the moiety ##STR2## wherein Ac is carboxacyl or an acyl group of formula: ##STR3## wherein Z is hydrogen, lower alkyl or a protective group removable by hydrogenolysis; R.sub.5 is lower alkyl; R.sub.1 and R.sub.2 when together are the divalent group; ##STR4## wherein Z and R.sub.5 are as defined above; R.sub.3 is hydrogen when R.sub.1 and R.sub.2 are taken together and is a monovalent thio group of formula: ##STR5## located in the 7(S)-position when R.sub.1 and R.sub.2 are taken independently, A represents hydrogen or hydroxyl, B represents hydrogen or hydroxyalkyl, n is the integer 0 when B is hydroxyalkyl and n is an integer of 0 to 1, inclusive, when B is hydrogen, X is oxygen .[.or sulfur.]., D is the acyl radical of a lower hydrocarbon carboxylic acid; R.sub.4 is lower alkyl and Y is carboxacyl or hydrogen.