Patents Represented by Attorney, Agent or Law Firm Bruce Vrana
  • Patent number: 8304607
    Abstract: The presently disclosed subject matter includes nucleic acid sequences and expression cassettes that contain regulatory sequences derived from Solanum tuberosum chitinase C genes, for expression of recombinant gene products in plants. The expression cassette drives high transgene expression in the epidermal (L1) cell layer.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: November 6, 2012
    Assignee: Syngenta Participations AG
    Inventors: Michael Nuccio, A. Todd Richmond
  • Patent number: 8115058
    Abstract: The present invention provides promoters from plants capable of driving gene expression in plant cells. The promoters vary in strength and in tissue specificity, and can be used to facilitate the development of transgenic plants in which tissue preferred expression, constitutive expression, and the strength of transgene expression is either more or less critical.
    Type: Grant
    Filed: May 23, 2011
    Date of Patent: February 14, 2012
    Assignee: Syngenta Participations AG
    Inventors: Paul Budworth, Todd Moughamer, Steven P. Briggs, Bret Cooper, Jane Glazebrook, Stephen A. Goff, Fumiaki Katagiri, Joel Kreps, Nicholas Provart, Darrell Ricke, Tong Zhu
  • Patent number: 8058419
    Abstract: The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given transgenic plant. The present invention is also drawn to DNA molecules comprising the promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
    Type: Grant
    Filed: January 19, 2010
    Date of Patent: November 15, 2011
    Assignee: Syngenta Participations AG
    Inventors: Stephen B. Milligan, Dale Skalla, Kay Lawton
  • Patent number: 8058421
    Abstract: The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given transgenic plant. The present invention is also drawn to DNA molecules comprising the promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
    Type: Grant
    Filed: January 19, 2010
    Date of Patent: November 15, 2011
    Assignee: Syngenta Participations AG
    Inventors: Stephen B. Milligan, Dale Skalla, Kay Lawton
  • Patent number: 8058420
    Abstract: The present invention is directed to promoters isolated from maize and functional equivalents thereto. The promoters of the present invention have particular utility in driving root-specific expression of heterologous genes that impart increased agronomic, horticultural and/or pesticidal characteristics to a given transgenic plant. The present invention is also drawn to DNA molecules comprising the promoters of the invention and transformed plant tissues containing DNA molecules comprising a promoter of the invention operably linked to a heterologous gene or genes, and seeds thereof.
    Type: Grant
    Filed: January 19, 2010
    Date of Patent: November 15, 2011
    Assignee: Syngenta Participations AG
    Inventors: Stephen B. Milligan, Dale Skalla, Kay Lawton
  • Patent number: 7957916
    Abstract: Methods, systems, and computer program products for generating theoretical mass spectral fragmentation patterns of a chemical structure is provided. The method includes obtaining a description of a chemical structure and generating, from the description, a list of chemical structure information. A binary tree data structure is used to organize the list of chemical structure information. The binary tree data structure may be fragmented by determining, based on a set of predetermined rules, a fragmentation point between two nodes in the binary tree data structure thereby dividing the binary tree data structure into a fragment and a complement. The molecular formula and molecular weight of each fragment is determined. The binary tree data structure is traversed and appropriate fragmentation rules are applied to produce a plurality of theoretical molecular fragments.
    Type: Grant
    Filed: January 28, 2010
    Date of Patent: June 7, 2011
    Assignee: Syngenta Participations AG
    Inventors: Lynde J. Nottebaum, Thomas D. McClure
  • Patent number: 7816151
    Abstract: Reactors and methods for miniaturized reactions having enhanced reaction kinetics. In particular the subject matter is directed to chemical and biological reactions conducted in a nanoporous membrane environment. The subject matter contemplates methods for modifying the kinetics of reactions and devices for conducting reactions having modified kinetics. The subject matter also provides systems for rapid miniaturized reactions. Further the subject matter includes methods and kits for conducting a reaction with enhanced throughput and methods of conducting miniaturized, high throughput analyses of reaction products, and the like. Reactions performed on or within a nanoporous membrane exhibits improved kinetic characteristics.
    Type: Grant
    Filed: August 8, 2005
    Date of Patent: October 19, 2010
    Assignee: Syngenta Participations AG
    Inventors: Andras Guttman, Zsolt Ronai, Csaba Barta
  • Patent number: 7801684
    Abstract: Methods, systems, and computer program products for generating theoretical mass spectral fragmentation patterns of a chemical structure is provided. The method includes obtaining a description of a chemical structure and generating, from the description, a list of chemical structure information. A binary tree data structure is used to organize the list of chemical structure information. The binary tree data structure may be fragmented by determining, based on a set of predetermined rules, a fragmentation point between two nodes in the binary tree data structure thereby dividing the binary tree data structure into a fragment and a complement. The molecular formula and molecular weight of each fragment is determined. The binary tree data structure is traversed and appropriate fragmentation rules are applied to produce a plurality of theoretical molecular fragments.
    Type: Grant
    Filed: April 22, 2005
    Date of Patent: September 21, 2010
    Assignee: Syngenta Participations AG
    Inventors: Lynde J. Nottebaum, Thomas D. McClure
  • Patent number: 7795502
    Abstract: This invention describes novel DNA sequences that function as promoters of transcription of associated nucleotide sequences. More specifically, this invention describes DNA sequences conferring constitutive expression to an associated nucleotide sequence. The invention also describes recombinant sequences containing such promoter sequences. The said recombinant DNA sequences may be used to create transgenic plants, but especially transgenic plants expressing a nucleotide sequence of interest at all times and in most tissues and organs.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: September 14, 2010
    Assignee: Syngenta Participations AG
    Inventors: Andrea Barta, Sergiy Lopato, Maria Kalyna
  • Patent number: 7777099
    Abstract: The present invention describes a method of increasing plan yield. Also described are DNA constructs comprising DNA sequences coding for proteins involved in sucrose transport, metabolism and uptake operably linked to controllable promoter regions and plants transformed with said constructs. More particularly a method for the controlled production of said proteins resulting in an alteration in plant growth characteristics, flowering time and in yield is described.
    Type: Grant
    Filed: December 8, 2008
    Date of Patent: August 17, 2010
    Assignee: Syngenta Limited
    Inventors: Chengcai Chu, Nan Qu, Uwe Sonnewald, Ian Jepson
  • Patent number: 7715990
    Abstract: Individual probes on micro-arrays are re-scaled and corrected with a set of probe dependent coefficients derived from genomic-DNA hybridization signals. A dynamic range for gDNA binding is determined by measuring a concentration signal curve. Signals for each probe are measured during multiple hybridizations within a linear range. Concentration insensitive probes are then found for two sets of experiments. Probes are discarded based on a threshold compared to their standard deviation divided by their average in each set. The correction coefficients are used to calculate a corrected intensity for each probe. Probes having high uncertainty (0.5 in one embodiment) are discarded. A weighting factor for each probe is determined along with an uncertainty factor. Finally, a call for each gene is made, such as absent, marginal or present.
    Type: Grant
    Filed: January 17, 2003
    Date of Patent: May 11, 2010
    Assignee: Syngenta Participations AG
    Inventors: Guangzhou Zou, Hur-Song Chang, Yiping Fan, Fan Long, Xun Wang, Tong Zhu
  • Patent number: 7640075
    Abstract: An apparatus and method is provided for coordinating automated package and bulk dispensing at a remote site. A hopper apparatus includes a series of storage compartments and access doors. The compartments and doors are linked to a PLC that is further linked to an inventory provider. The inventory provider takes product orders from an end-user. The end-user is provided an end-user access code. The inventory provider communicates with the PLC and reserves for the ordered product(s) a vacant storage compartment(s). The inventory provider delivers the product(s) ordered by the end-user to the hopper apparatus. Upon delivery, the inventory provider enters the appropriate end-user access code(s), causing the PLC to open the storage compartment(s) previously reserved by the inventory provider for the products ordered by the end-user. The inventory provider loads the appropriate storage compartment(s) with the end-user product(s).
    Type: Grant
    Filed: January 17, 2006
    Date of Patent: December 29, 2009
    Assignee: Syngenta Participations AG
    Inventor: Gary W. Wietgrefe
  • Patent number: 7615624
    Abstract: The invention provides a method to identify a plurality of plant promoters having specified characteristics and promoters identified by the method. The plant genus from which at least some of the promoters are derived is Arabidopsis. Also provided are transgenic plants comprising the genes identified by the methods of the invention.
    Type: Grant
    Filed: January 18, 2006
    Date of Patent: November 10, 2009
    Assignee: Syngenta Participations AG
    Inventors: Paul Budworth, Devon Brown, Sherman (Hur-Song) Chang, Bin Han, Xun Wang, Bret Cooper, Tong Zhu
  • Patent number: 7550578
    Abstract: The present invention provides promoters from plants capable of driving gene expression in plant cells. The promoters vary in strength and in tissue specificity, and can be used to facilitate the development of transgenic plants in which tissue preferred expression, constitutive expression, and the strength of transgene expression is either more or less critical.
    Type: Grant
    Filed: October 18, 2005
    Date of Patent: June 23, 2009
    Assignee: Syngenta Participations AG
    Inventors: Paul Budworth, Todd Moughamer, Steven P. Briggs, Bret Cooper, Jane Glazebrook, Stephen A. Goff, Fumiaki Katagiri, Joel Kreps, Nicholas Provart, Darrell Ricke, Tong Zhu
  • Patent number: 7470831
    Abstract: The present invention describes a method of increasing plan yield. Also described are DNA constructs comprising DNA sequences coding for proteins involved in sucrose transport, metabolism and uptake operably linked to controllable promoter regions and plants transformed with said constructs. More particularly a method for the controlled production of said proteins resulting in an alteration in plant growth characteristics, flowering time and in yield is described.
    Type: Grant
    Filed: December 10, 1998
    Date of Patent: December 30, 2008
    Assignee: Syngenta Limited
    Inventors: Chengcai Chu, Nan Qu, Uwe Sonnewald, Ian Jepson
  • Patent number: PP18754
    Abstract: A new and distinct cultivar of Asteriscus maritimus plant named ‘Asmago’ characterized by its earliness, flat mounding growth habit, large golden yellow flowers, silvery colored leaves and good branching.
    Type: Grant
    Filed: June 26, 2006
    Date of Patent: April 22, 2008
    Assignee: Syngenta Seeds B.V.
    Inventor: Anna M. W. P. Houbraken
  • Patent number: PP18871
    Abstract: A new and distinct cultivar of New Guinea Impatiens plant named ‘Ingfilu’ characterized by its large white with pink blotch colored flowers with small, dark green foliage, early flowering, good heat tolerance, nice rounded shaped growth habit with excellent basal branching and good vigor.
    Type: Grant
    Filed: May 22, 2006
    Date of Patent: June 3, 2008
    Assignee: Syngenta Seeds B.V.
    Inventor: Monica Maria Adelheid Sanders
  • Patent number: PP18872
    Abstract: A new Osteospermum plant particularly distinguished by its spreading character and large white flower heads.
    Type: Grant
    Filed: October 17, 2006
    Date of Patent: June 3, 2008
    Assignee: Syngenta Seeds B.V.
    Inventor: Anna M. W. P. Houbraken
  • Patent number: PP18873
    Abstract: A new Osteospermum plant particularly distinguished by its spreading character, good summer performance and light purple flowers.
    Type: Grant
    Filed: October 16, 2006
    Date of Patent: June 3, 2008
    Assignee: Syngenta Seeds B.V.
    Inventor: Anna M. W. P. Houbraken
  • Patent number: PP18875
    Abstract: A new Osteospermum plant particularly distinguished by its compact round plant habit, spoon flower character and nice purple color at the rolled petals in the spoon.
    Type: Grant
    Filed: October 16, 2006
    Date of Patent: June 3, 2008
    Assignee: Syngenta Seeds B.V.
    Inventor: Anna M. W. P. Houbraken