Abstract: Methods and compositions for staining based upon nucleic acid sequence that employ nucleic acid probes are provided. Said methods produce staining patterns that can be tailored for specific cytogenetic analyses. Said probes are appropriate for in situ hybridization and stain both interphase and metaphase chromosomal material with reliable signals. The nucleic acid probes are typically of a complexity greater than 50 kb, the complexity depending upon the cytogenetic application. Methods and reagents are provided for the detection of genetic rearrangements. Probes and test kits are provided for use in detecting genetic rearrangements, particularly for use in tumor cytogenetics, in the detection of disease related loci, specifically cancer, such as chronic myelogenous leukemia (CML), retinoblastoma, ovarian and uterine cancers, and for biological dosimetry.

Abstract: A gasket is capable of providing an excellent slidabiity and holding its sealability without applying lubricant and a gasket that can prevent a resin film from being peeled off of a gasket body and prevent the generation of a molding defect such as pinholes. The gasket can be installed slidably in a outer tube of a syringe, including a gasket body and a resin film formed of a material lower in coefficient of friction than a material of the gasket body, which covers at least an outer periphery of the gasket body, in which when a surface roughness of the resin film on the outer tube side is defined as Ra1 and a surface roughness of the resin film on the gasket body side is defined as Ra2, a relationship of 1.5 Ra1?Ra2 is satisfied.

Abstract: A support information communication system for transferring requests for information support that is to be used by personnel performing servicing, mounting and/or dismounting of a bearing and/or a seal. The system includes one or more information terminals and an information support computer.

Abstract: A disposable aerosol generator for use with an inhaler device which includes a heater adapted to volatilize fluid stored in the disposable aerosol generator and method of using the inhaler. The disposable body includes a sealed chamber and an outlet, the chamber being located between first and second layers of material. The chamber holds a predetermined volume of a fluid which is expelled through the outlet when the fluid in the chamber is volatilized by the heater. The disposable body can include a series of spaced apart aerosol generators, each of which can be advanced to a release position at which the heater can heat one of the fluid containing chambers. Prior to heating the fluid, the outlet can be formed by severing the first and/or second layer with a piercing element and the volatilized fluid can be expelled from the outlet into a passage of a dispensing member.

Abstract: A filter making apparatus includes a positioning device having a passageway therethrough, with the passageway guiding a continuous flavor element such as a continuous strand of textile material from an inlet of the passageway to an outlet of the passageway. A liquid flavorant is introduced into the passageway at a desired flow rate and the strand of material carries the supplied liquid flavorant out of the positioning device at a rate substantially equal to the desired flow rate. A portion of the passageway can form a bath of the liquid flavorant supplied to the passageway through a separate inlet at approximately atmospheric pressure. A portion of the positioning device guides the continuous strand of material through the bath, or guides the strand to pass along the bottom of the passageway, and the saturated or partially saturated strand of material then exits from an outlet of the passageway to a point in the path of filter tow material that is being converged to form a filter rod.

Abstract: A NF-?B inhibitor represented by the following formula (I) is provided: ?

Abstract: A parking assist device (1) includes a camera (3) for capturing an image of an exterior of a vehicle, and a monitor (4) for displaying the captured image, and sets a target parking position by moving a target parking frame (11) displayed on a screen of the monitor (4). A default position of the target parking frame (11) is determined based on a target parking position (P2) which is a relative position with respect to a parking preparation position (P1). The target parking position (P2) is estimated based on a running state of the vehicle until the vehicle reaches the parking preparation position (P1).

Abstract: Biofilm forming organisms are incubated to form a biofilm on projections by providing a flow of liquid growth medium across projections, the direction of the flow of liquid being repeatedly changed, and an assay made of the resulting biofilm. Biofilm forming organisms are incubated to form a biofilm on projections arranged in rows, with several projections in each row, while providing a flow of liquid growth medium across each row of projections, and an assay made of the resulting biofilm. Sensitivity of the biofilm to antimicrobial reagent may be determined by treating the projections with antimicrobial reagent before carrying out the assay, by treating each row of projections with a different antimicrobial reagent, and each of the projections in a row with a different concentration of antimicrobial reagent.

Abstract: A method for the automated optimization of an injection molding machine set-up process comprising injection molding one or more parts, inspecting the parts for defects, adjusting the injection stroke and/or the injection velocity and repeating the process until the defects are reduced. There is also disclosed a method comprising injection molding one or more parts, determining a mean injection pressure profile by measuring the injection pressure with the machine configured with a constant, desired injection velocity. Then the velocity profile is adjusted to reduce differences between the measured pressure and the mean pressure profile. A further method is disclosed wherein the kickback is calculated and adjusted from screw displacement, packing/holding time and pressure. Also disclosed is a method comprising injection molding one or more parts then determining the gate freeze time by incrementing the holding time and measuring the screw displacement.

Abstract: A cutting insert comprises first and second polygonally-shaped main faces arranged substantially parallel to one another, and a side face structure interconnecting the first and second main faces to define a peripheral edge. At least the first main face includes at least one projection extending to the peripheral edge, the projection formed by: a portion of the first main surface (defining a relief surface), a portion of the side face structure (defining a rake surface), and a portion of the peripheral edge (defining a cutting edge). The insert includes support surfaces defined by a portion of the second main face, and by portions of the side surface structure other than the rake surface.

Abstract: A diffusing film comprises a transparent resin in which scatterers are dispersed. The difference between the refractive index of the transparent resin and that of the scatterers is in the range of 0.04 to 1.5. The scatterers are flat particles having sizes of 0.1 to 50 ?m.

Abstract: A power-residue calculating circuit includes: an I/F (interface) circuit with respect to an external bus; an e register holding a key e; a Y register holding a multiplier Y for Montgomery conversion; an N register holding a key N; a B2N register holding a value of (2B+N) calculated during the Montgomery conversion; an X register holding a plaintext X; a calculating circuit performing calculations for encryption and decryption; a P register holding a calculation result P; a power-residue control circuit serving as a state machine when the power-residue calculation is performed; a Montgomery multiplication residue/residue control circuit serving as a state machine when the Montgomery multiplication residue calculation and residue calculation are performed; and an addition/subtraction control circuit controlling calculations addition and subtraction.

Abstract: The present invention provides a planographic printing plate precursor comprising a photosensitive layer on a support, the photosensitive layer including an infrared absorbent, a radical polymerization initiator and a radical polymerizing compound, the photosensitive layer being recordable with irradiation with an infrared ray, and being at least one of soluble and dispersible in water.

Abstract: An apparatus for chip removing machining includes first and second parts which are intercoupled by a coupling. The coupling includes two interacting surfaces disposed on the first and second parts, respectively. The interacting surfaces are profiled to intermesh with one another to define an intermeshing region of the coupling. Each of the surfaces is profiled with first and second sets of grooves which define first and second main directions, respectively, which extend transversely to one another. At least one groove on each of the surfaces extends across less than the entire intermeshing region, wherein the surfaces define only one coupling position for the first and second parts.

Abstract: An optical recording medium having a phase transition material film and a method of manufacturing the optical recording medium are provided. In the method, first, a phase transition material film, a sacrificial film, and a metal film are sequentially stacked on a substrate. Next, the metal film is anodized to form a metal oxide film having a plurality of holes, and portions of the sacrificial film exposed through the holes are anode-oxidized to form oxide films. Thereafter, the phase transition material film is patterned by removing the metal oxide film and by etching the sacrificial film and the phase transition material film using the oxide films as a mask. Then, the oxide films are removed from the sacrificial film, and an upper insulation film, a reflection film, and a protection film are deposited on the upper surface of the patterned phase transition material film.

Abstract: An optical information recording medium is here disclosed which comprises a transparent substrate, a recording layer comprising an organic dyestuff on which information can be written by a laser beam, a reflective layer and a protective layer formed in this order on the substrate, the aforesaid optical information recording medium being characterized by containing a pit-edge control agent for the formation of recording pits, particularly a dyestuff thermal decomposition accelerator in the recording layer. By the addition of the pit-edge control agent, deviation properties and jitter properties can be remarkably improved, whereby a CD-R medium having a low error rate and good recording properties can be provided. In consequence, stable compatibility with a commercial CD player can be secured.

Abstract: A new and distinct Floribunda rose plant is provided that forms on a nearly continuous basis attractive bright yellow-orange blossoms. The growth habit is vigorous and bushy. The semi-glossy foliage is dense, dark green and of good substance and contrasts nicely with the yellow-orange blossom coloration. Very good tolerance to Black Spot and Oidium is displayed under normal growing conditions. The plant is well suited for growing as attractive ornamentation in parks and gardens.

Abstract: A new and distinct variety of rose plant of the Floribunda Class is provided which abundantly forms on a nearly continuous basis attractive semi-double self-cleaning blossoms with reflexed yellow-orange petals that are strongly bordered in red. A very short time between bloom cycles is observed. The growth habit is vigorous, compact, and bushy. Dark green glossy foliage is formed in abundance that contrasts nicely with the blossom coloration. Above average disease resistance, especially with respect to Black Spot is displayed. The blossoms possess a slight spice fragrance, and no hips have formed during observations to date. The new variety is well suited for providing distinctive ornamentation in the garden.

Abstract: A vehicle drive system includes a compact drive mode-shifting mechanism that is mounted in the final drive gearset of a vehicle. The drive mode-shifting mechanism includes a first shaft, a second shaft, and a clutch assembly. The first shaft forms an input shaft for the differential for a pair of wheels, the second shaft transmits engine power and the clutch assembly connects and disconnects the first and second shafts to one another to effect either the two-wheel-drive mode or the four-wheel-drive mode. The first shaft has an outer surface provided with a first spline, the second shaft has an outer surface provided with a second spline, and said clutch assembly includes an axially movable shifting member provided with an internal spline.

Abstract: Method and apparatus for treatment and post-treatment of the stenosed region of an artery after reduction of the region by angioplasty or other means by applying a radioactive dose to said reduced region of the artery by positioning a radioactive dose to the reduced region is disclosed.