Abstract: Disclosed are biological reagents which comprise compounds that inhibit &bgr;-amyloid peptide release and/or its synthesis, and, accordingly, have utility in determining the cellular mechanism involved in the generation of &bgr;-amyloid peptide.
Type:
Grant
Filed:
September 29, 1999
Date of Patent:
November 26, 2002
Assignees:
Elan Pharmaceuticals Inc., Eli Lilly & Company
Inventors:
James E. Audia, Paul A. Hyslop, Jeffrey S. Nissen, Richard C. Thompson, Jay S. Tung, Laura I. Tanner