Patents Represented by Attorney C. F. Costello, Jr.
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Patent number: 5942640Abstract: The present invention provides an efficient, economic and ecologically sound process for the manufacture of a compound of formula I via the reaction of a suitable acid halide and an appropriate amine in the presence of aqueous carbonate or bicarbonate or a mixture thereof and optionally in the presence of a co-solvent.Type: GrantFiled: April 20, 1998Date of Patent: August 24, 1999Assignee: American Cyanamid CompanyInventors: Albert Anthony Cevasco, Kenneth Alfred Martin Kremer
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Patent number: 5591693Abstract: The present invention relates to chemical compositions comprising imidazolinone compounds that are suitable for use in turfgrass management. The invention also provides methods for altering the growth and reducing mowing frequency, suppressing seed head formation and controlling undesirable vegetation in turfgrass.Type: GrantFiled: May 2, 1994Date of Patent: January 7, 1997Assignee: American Cyanamid CompanyInventors: Prithvi R. Bhalla, Robert M. Herrick, Donald W. Gates
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Patent number: 5491160Abstract: A pesticidal composition which includes a substituted 1,2,4-triazole compound and a pyrethroid insecticide is disclosed. The pesticidal composition is particularly effective against aphid pests.Type: GrantFiled: October 4, 1994Date of Patent: February 13, 1996Assignee: American Cyanamid Co.Inventors: Robert J. Knight, David P. Highwood
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Patent number: 5425737Abstract: A purse string suturing instrument is provided for quickly and effectively forming a purse string suture in tubular tissue through relatively small cannulas placed in the body. The instrument includes a pair of elongated jaws, each having a row of spaced-apart uniform-size teeth. The jaws are hinged together at one end to clamp the tubular tissue therebetween. The two rows of teeth are offset with respect to each other so that they mesh when the jaws are closed. A single operating mechanism is provided to articulate the pair of jaws with respect to a longitudinal axis of the suturing instrument and actuate the jaws between an open position and a clamping position. The jaws are inserted through a cannula and positioned to close around the tissue to be sutured. The rows of teeth bend the tissue therebetween into a wavelike configuration. A pair of needles, the ends of each being connected to a single length of suture, is then inserted through passageways provided through the teeth.Type: GrantFiled: July 9, 1993Date of Patent: June 20, 1995Assignee: American Cyanamid Co.Inventors: John E. Burbank, William J. Allen, George Jessup, Frederick F. Ahari, Robert A. Rabiner
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Patent number: 5425738Abstract: An endoscopic insertion device for inserting an anastomosis ring having two unitary members in an anatomic tubular body member comprises an anastomosis ring adapter for mounting the unitary members in an engaging position, an inserter for inserting the ring adapter in the tubular body member, and an actuator for actuating the adapter to close the anastomosis ring. A method of using the endoscopic insertion device includes the steps of inserting the anastomosis ring in an engaged position into the tubular body member, securing opposite ends of the tubular body member to the engaged anastomosis ring, applying a biasing force to close the anastomosis ring, releasing the biasing force, and axially withdrawing the insertion device from the closed anastomosis ring.Type: GrantFiled: October 18, 1993Date of Patent: June 20, 1995Assignee: American Cyanamid CompanyInventors: Scott B. Gustafson, Frederick Ahari, William J. Allen, George Jessup, John F. Howard, Harold S. Terk, Lester F. Miller
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Patent number: 5411521Abstract: A single-strike die mechanism includes a rotatable cam drive ring driven to impart through a cam mechanism linear motion to at least three crimping dies. The crimping dies are symmetrically arranged within a die guide and simultaneously actuated to move in a radial direction toward a centerline of a surgical needle. A surgical suture is axially inserted within a hollow barrel end of the needle, and the barrel end is crimped by the crimping dies to secure the suture therein. A method for operating the single-strike die mechanizes the procedure for securing the suture within the barrel end of the needle.Type: GrantFiled: May 4, 1993Date of Patent: May 2, 1995Assignee: American Cyanamid CompanyInventors: Charles L. Putnam, Mark L. Stein, Patrick R. Holmes
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Patent number: 5403344Abstract: A surgical suturing needle has a tapered needle head with a multi-faceted cross-section. The cross-section is formed by three circumferentially-spaced cutting edges formed at a primary angle and a plurality of extended legs, each extending from one of the primary angles and formed at a secondary angle. In addition, a plurality of connecting surfaces adjoin adjacent extended legs.Type: GrantFiled: July 22, 1993Date of Patent: April 4, 1995Assignee: American Cyanamid Co.Inventor: Richard C. Allen
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Patent number: 5376102Abstract: A deformable surgical repair device is manufactured from a block or graft copolymer. The copolymer comprises a plurality of first linkages selected from the group consisting of glycolic acid ester and lactic acid ester linkages, and mixtures thereof, and a plurality of second linkages selected from the group consisting of 1,3-dioxan-2-one; 1,4-dioxan-2-one and .epsilon.-caprolactone linkages. The plurality of first linkages comprises at least about 50 up to about 90 mole percent of the copolymer. In an alternative Claim, the deformable surgical repair device is manufactured from a blend of a first and a second absorbable polymer. The first absorbable polymer comprises a plurality of linkages selected from the group consisting of glycolic acid ester and lactic acid ester linkages, and mixtures thereof. The second absorbable polymer comprises a plurality of linkages selected from the group consisting of 1,3-dioxan-2-one; 1,4-dioxan-2-one and .epsilon.-caprolactone linkages.Type: GrantFiled: January 13, 1992Date of Patent: December 27, 1994Assignee: American Cyanamid Co.Inventors: Peter K. Jarrett, Donald J. Casey
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Patent number: 5372251Abstract: An improved surgical suture package has a back panel and a cover flap foldably connected to one side of the back panel. The back panel and cover flap each have a coordinating surface. The improvement comprises a plurality of embossed patterns on the coordinating surfaces of the back panel and cover flap.Type: GrantFiled: August 3, 1992Date of Patent: December 13, 1994Assignee: American Cyanamid Co.Inventor: Robert F. Thompson
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Patent number: 5352515Abstract: This invention relates to materials medical or veterinary use that possess considerably improved properties with regard to friction. The invention also relates to the production of such materials from existing materials that possess suitable bulk properties, but inappropriate frictional properties. This invention also relates to a hydrophilic coating material that provides improved frictional properties.Type: GrantFiled: March 2, 1992Date of Patent: October 4, 1994Assignee: American Cyanamid CompanyInventors: Peter K. Jarrett, George Jessup, Louis Rosati, Chris Martin, John W. Maney
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Patent number: 5342395Abstract: A load-bearing, bioabsorbable surgical repair device manufactured from a copolymer having a plurality of first linkages of lactide or lactide/glycolide, and a plurality of second linkages of a polymer having a glass transition temperature below ambient temperature. The second linkages preferably are selected from: 1,3-dioxan-2-one; 1,4-dioxan-2-one; and .epsilon.-caprolactone.Type: GrantFiled: January 13, 1992Date of Patent: August 30, 1994Assignee: American Cyanamid Co.Inventors: Peter K. Jarrett, Donald J. Casey, Louis Rosati
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Patent number: 4630617Abstract: A surgical electrode consisting of an insulated stainless steel wire having surgical needles conductively affixed at one or both ends, at least one needle having a pointed end and a nonpointed end with a blind hole or flange in the nonpointed end thereof, and the blunt end of a blunt pointed pin fitted into said hole or flange and a crimp in said nonpointed end of the needle retaining said pin in said hole or flange with controlled pull-out characteristics, said pin conductively and permanently affixed at the other end to said wire, whereby said pin may be pulled out of said blind hole or flange and the blunt end of said pin used as an electrical jack for connection to a pacemaker or similar electric current generating or monitoring device. The electrodes are particularly useful as temporary heart pacer electrodes for cardiac stimulation during and after surgical operations.Type: GrantFiled: October 9, 1980Date of Patent: December 23, 1986Assignee: American Cyanamid CompanyInventors: Thomas A. Ritter, James C. Bray, Alan L. Kaganov
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Patent number: 4474758Abstract: A combined vaccine for eliciting polyribosyl ribitol phosphate (PRP) antibody formations in warm-blooded animals has been invented. The combined vaccine comprises the capsular polysaccharide PRP isolated and purified from Haemophilus influenzae type b and antigens isolated and purified from an outer membrane component of Bordetella pertussis.A method for inducing active immunization in warm-blooded animals against systemic infection caused by the pathogen H. influenzae type b has also been invented. The method comprises administering an immunogenic amount of a combined vaccine comprising the capsular polysaccharide PRP isolated and purified from H. influenzae type b and antigens isolated and purified from an outer membrane component of B. pertussis.Type: GrantFiled: November 19, 1981Date of Patent: October 2, 1984Assignee: American Cyanamid CompanyInventors: Joseph S. C. Kuo, Nobuo Monji
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Patent number: 4102738Abstract: Chitosan is used to improve the flat crush resistance of corrugating medium. A solution of chitosan in dilute acid is added to corrugating medium pulp containing at least about 0.05%, based on the dry fiber weight, of spent semichemical pulping liquor. The corrugating medium pulp is then formed into corrugating medium sheets, dried and manufactured into corrugating medium.Type: GrantFiled: January 17, 1977Date of Patent: July 25, 1978Assignee: American Cyanamid CompanyInventor: John A. Dzurik
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Patent number: 3997657Abstract: A dry diagnostic reagent composed of specially prepared, fixed and stabilized fetal calf thymocytes on microscope slides ready for use in an immunofluorescent test for the detection of human anti-nuclear factor in human serum or plasma in the diagnosis of systemic lupus erythematosus and other autoimmune diseases.Type: GrantFiled: December 3, 1975Date of Patent: December 14, 1976Assignee: American Cyanamid CompanyInventors: Beatrice Frances Dziobkowski, Gerald Earl Stiles
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Patent number: 3992249Abstract: The deposition of adhesive pitch particles from aqueous suspension of cellulose fibers is inhibited and, if desired, substantially prevented, from depositing on the surfaces of pulp-making equipment by adding to the suspension an anionic polymer containing at least about 25 mol percent but not more than about 85 mol percent of hydrophobic oleophilic linkages selected from the group comprising styrene, isobutylene, methylstyrene, allyl stearate, octadecyl acrylate, octadecene, dodecene, n-octadecylacrylamide, vinyl stearate and vinyl dodecyl ether and at least about 15 mol percent but not more than about 75 mol percent of hydrophilic acid linkages selected from the group comprising acrylic acid, methacrylic acid, maleic acid, itaconic acid, acrylamidoacetic acid, maleamic acid and styrenesulfonic acid, forming a pitch-polymer complex of said particles and said polymer, and removing said complex with the water used to wash said cellulose fiber suspension thereby separating substantially all of the pitch-polymerType: GrantFiled: December 8, 1975Date of Patent: November 16, 1976Assignee: American Cyanamid CompanyInventor: Charles Edward Farley
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Patent number: 3991200Abstract: The use of substituted nitroimidazolyl-thiadiazoles and oxadiazoles are described along with methods of administration of the same. These compounds are active in enhancing the growth rate of warm-blooded animals and in controlling the growth of pathogenic microorganisms such as bacteria.Type: GrantFiled: March 27, 1973Date of Patent: November 9, 1976Assignee: American Cyanamid CompanyInventors: Gerald Berkelhammer, Goro Asato