Abstract: Provided are differential antibodies recognizing the cleaved and non-cleaved forms of matrix metalloproteinases (MMPs), and methods of using the antibodies as surrogate diagnostic markers for the presence of active MMPs in cancer, such as growing breast cancers.
Type:
Grant
Filed:
December 11, 2008
Date of Patent:
January 8, 2013
Assignee:
Wayne State University
Inventors:
Avraham Raz, Pratima Nangia-Makker, Rafael Fridman