Abstract: Novel rhodamine dye compounds, labelled conjugates comprising the dyes are described, together with methods for their use. The dyes and labelled conjugates are useful as molecular probes in a variety of applications, such as in assays involving staining of cells, protein binding, and analysis of nucleic acids, such as hybridization assays and nucleic acid sequencing.
Type:
Grant
Filed:
May 16, 2007
Date of Patent:
May 15, 2012
Assignee:
Illumina Cambridge Limited
Inventors:
Colin Barnes, Nikolai Nikolaevich Romanov
Abstract: Described herein are systems and methods for normalizing data without the use of external controls. Also described herein are systems and methods for analyzing cluster data, such as genotyping data, using an artificial neural network.