Patents Represented by Attorney Cara M. Coburn

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  • Antibodies that bind hepatocyte growth factor activator
    Patent number: 7825221
    Abstract: The invention provides methods and compositions for modulating hepatocyte growth factor activator function.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: November 2, 2010
    Assignee: Genentech, Inc.
    Inventors: Daniel K. Kirchhofer, Yan Wu
  • Anti-EphB2 antibodies and methods using same
    Patent number: 7767205
    Abstract: The invention provides anti-EphB2 antibodies, immunoconjugates, and compositions comprising and methods of using these antibodies and immunoconjugates.
    Type: Grant
    Filed: July 31, 2007
    Date of Patent: August 3, 2010
    Assignee: Genentech, Inc.
    Inventors: Weiguang Mao, Paul Polakis
  • HGF beta chain variants
    Patent number: 7737115
    Abstract: The invention provides HGF/Met modulators comprising HGF having mutations in regions that affect HGF function, and antagonists that target said regions. The invention further provides methods of identifying, making and using these modulators.
    Type: Grant
    Filed: April 17, 2006
    Date of Patent: June 15, 2010
    Assignee: Genetech, Inc.
    Inventors: Daniel K. Kirchhofer, Robert A. Lazarus, Christian Wiesmann
  • Methods and compositions for modulating hyperstabilized c-met
    Patent number: 7615529
    Abstract: The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by inhibiting a hyperstabilized c-met protein.
    Type: Grant
    Filed: March 24, 2006
    Date of Patent: November 10, 2009
    Assignee: Genentech, Inc.
    Inventors: Monica Kong-Beltran, Dineli M. Wickramasinghe
  • Humanized anti-cmet antibodies
    Patent number: 7476724
    Abstract: The invention provides therapeutic anti-c-met antibodies, and compositions comprising and methods of using these antibodies.
    Type: Grant
    Filed: August 4, 2005
    Date of Patent: January 13, 2009
    Assignee: Genentech, Inc.
    Inventors: Mark S. Dennis, Karen Billeci, Judy Young, Zhong Zheng
  • Methods and compositions for modulating hepatocyte growth factor activation
    Patent number: 7432044
    Abstract: The invention provides methods and compositions for modulating hepsin activity and the HGF/c-met signaling pathway, in particular by regulating pro-HGF activation by hepsin.
    Type: Grant
    Filed: July 25, 2005
    Date of Patent: October 7, 2008
    Assignee: Genentech, Inc.
    Inventors: Daniel K. Kirchhofer, Paul M. Moran, Mark D. Peek