Abstract: The present invention provides new anti-?5?1 antibodies, compositions and kits comprising the antibodies, and methods of making and using the antibodies.
Type:
Grant
Filed:
March 23, 2010
Date of Patent:
February 28, 2012
Assignee:
Genentech, Inc.
Inventors:
Wei-Ching Liang, Gregory D. Plowman, Yan Wu, Weilan Ye
Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumors of glial origin in mammals and to methods of using those compositions of matter for the same.
Abstract: The invention provides anti-Robo4 antibodies, and compositions comprising the antibodies and methods of using these antibodies, including diagnostic and therapeutic methods.
Type:
Grant
Filed:
February 8, 2008
Date of Patent:
November 16, 2010
Assignee:
Genentech, Inc.
Inventors:
Alexander W. Koch, Scott Stawicki, Yan Wu, Richard Carano, Franklin V. Peale, Jr., Ryan J. Watts
Abstract: The present invention involves the identification and preparation of vascular endothelial growth factor-E (VEGF-E). VEGF-E is a novel polypeptide related to vascular endothelial growth factor (VEGF) and bone morphogenetic protein 1. VEGF-E has homology to VEGF including conservation of the amino acids required for activity of VEGF. VEGF-E can be useful in wound repair, as well as in the generation and regeneration of tissue.