Abstract: An implantable medical device that includes an elongated body having a proximal end and a distal end, a helical fixation member extending from the distal end of the elongated body, the helical fixation member including a distal tip for affixing the distal end of the elongated body at an implant site, and a tracking member extending from the distal end of the elongated body, through the helical fixation member and outward from the distal tip of the helical fixation member for tracking along an implant pathway during implantation of the implantable medical device.

Abstract: A method for delivering physiological pacing includes selecting an electrode implant site within an interventricular septal zone, which is in proximity to the bundle of His where pacing stimulation results in a rhythm breaking out at an intrinsic location, and wherein a ratio of sensed P-wave amplitude to sensed R-wave amplitude is less than approximately 0.5 and a pacing threshold is less than or equal to approximately 1.5 volts.

Abstract: An implantable cell/tissue-based biosensor device detects and/or monitors the amount of one or more specific analytes within a patient. Stimulation circuitry stimulates the cells/tissue of the biosensor device causing the cells/tissue to evoke a response that is altered by the presence of a specific analyte. Sensing circuitry detects the evoked response and the amount of analyte is determined based on the detected response.

Abstract: A medical electrical electrode includes an elongated conductive coil located over a lead body, and a conductive polymer material in contact with the lead body and located between individual coils of the elongated conductive coil. In certain embodiments, the conductive polymer is a polymer (e.g., silicone) implanted with a conductive filler (e.g., carbon black). In certain embodiments, the conductive polymer material is generally isodiametric with an outer diameter of the individual coils of the elongated conductive coil. A medical electrical electrode is fabricated by sliding an elongated conductive coil over a length of a lead body, dispersing a conductive polymer on the helical coil, inserting a tubing over the elongated conductive coil, distributing the polymer material between individual turns of the elongated conductive coil, heating the tubing so the tubing shrinks around the elongated conductive coil, and removing the tubing.

Abstract: A determination of an equivalent series resistance (ESR) effect for high frequency filtering performance of a filtered feed-through assembly is described. A low frequency signal is introduced to a filtered feed-through assembly. ESR limit of the filtered feed-through is determined based on the low frequency signal.

Abstract: An improved system and method for placing implantable medical devices (IMDs) such as leads within the coronary sinus and branch veins is disclosed. In one embodiment, a slittable delivery sheath and a method of using the sheath are provided. The sheath includes a slittable hub, and a substantially straight body defining an inner lumen. The body comprises a shaft section and a distal section that is distal to, and softer than, the shaft section. A slittable braid extends adjacent to at least a portion of one of the shaft section and the distal section. In one embodiment of the invention, the sheath further includes a transition section that is distal to the shaft section, and proximal to the distal section. The transition section is softer than the shaft section, but stiffer than the distal section.

Abstract: An implantable medical device has one or more feedthrough/electrode assemblies positioned around an outer periphery of the device. Each of the assemblies includes a ferrule and a feedthrough conductor that extends longitudinally through the ferrule. Each of the assemblies also includes a cover having an insulative body and an electrical contact that is mounted to the plastic insulator. The plastic insulator is positioned over an inner end of the assembly such that the contact is operatively coupled to the feedthrough conductor of the assembly. The cover can be oriented so as to be freely accessible for purposes of electrically connecting circuitry within the implantable medical device to the contact, and in turn, the feedthrough conductor. In turn, the wiring used in connecting the circuitry and the contact can be routed within the implantable medical device as desired.

Abstract: An electrolytic capacitor cell for use in implantable medical devices and associated method for manufacture are provided. The capacitor cell includes an electrode substrate having a dielectric layer formed thereon by atomic layer deposition. In various embodiments, the dielectric layer includes an oxide of one or more valve metals.

Abstract: The separator subassembly includes a spacer layer formed from a film of microporous, non-conductive material joined to a separator by a heating process, wherein the separator is formed from an elongated piece of microporous, non-conductive film. When an anode subassembly is enveloped within the separator subassembly, the spacer aligns with a surface-mounted anode current collector of the alkali metal anode. The spacer serves as an additional protective layer between the cathode material and the anode current collector as the anode depletes.

Abstract: Methods and apparatus are provided for manufacturing a medical device. An implantable medical device includes a semiconductor substrate, an epitaxial layer, and a power transistor. The epitaxial layer overlies the semiconductor substrate. The power transistor is formed in the epitaxial layer and includes a first electrode, a control electrode, and a second electrode. The power transistor has a voltage breakdown greater than 100 volts. The current flow of the power transistor is vertical through the epitaxial layer to the semiconductor substrate. A backside contact couples to the first electrode of the power transistor. A method of manufacturing a medical device includes a power transistor formed in an epitaxial layer overlying a semiconductor substrate. A deep trench is etched through the epitaxial layer exposing the semiconductor substrate. A first electrode contact region couples to an exposed area of the semiconductor substrate in the deep trench.

Abstract: A medical electrical lead includes a conductive component coupling a coil to a wire or cable; the conductive component includes a first side, a second side, a first groove formed in the first side and a second groove formed in the second side. The first groove holds a portion of the cable and the second groove holds a portion of the coil.

Abstract: A capacitor including a flexible case and method for manufacturing the same are provided. The capacitor includes an electrode assembly encased in a sealed flexible case. The electrode assembly includes an anode formed from a high surface area valve metal and a cathode operatively positioned relative to the anode. The flexible case may conform to an exterior contour of the electrode assembly.

Abstract: Methods are provided for manufacturing an electrode. In one exemplary embodiment, the method includes the steps of contacting the silver layer with vanadium oxide, and heating the silver layer and vanadium oxide in an oxygen-containing atmosphere to form a silver vanadium oxide layer chemically bonded to the metal substrate.

Abstract: An electrochemical cell, comprising: an encasement including a case having a bottom and a sidewall terminating at an open top and a cover disposed over the case open top and hermetically sealed to the case, the encasement defining an interior space for containing cell components; and an access port defining at least one lumen extending through any of the case bottom, the case sidewall or the cover for receiving a liquid electrolyte, the access port being sealed closed after receiving the liquid electrolyte using a fusion welding method in the presence of the electrolyte.

Abstract: A deflectable stylet system optimized for use in conjunction with a lead of the type having a fixation helix that is screwed into body tissue by rotation of the lead's connector pin is disclosed. The system includes an attachment that is rotatable and longitudinally slidable with respect to the handle of a deflectable stylet. A lead coupled to the attachment may be moved longitudinally with respect to a stylet to account for slight variances in the lead length. In one embodiment, the attachment couples to the lead via a pushbutton mechanism that can be locked to the lead using one hand. The attachment may be rotated to thereby rotate the lead connector. This allows for retraction and extension of a retractable fixation helix, and for further attachment or detachment of a fixation helix to adjacent tissue. In one embodiment, the attachment may be longitudinally rigidly positioned in predetermined locations with respect to the handle.

Abstract: An optical feedthrough assembly is provided that is configured to be disposed through the canister of an implantable medical device. The optical feedthrough assembly comprises a ferrule having an aperture therethrough and an inner surface therethrough. An optical fiber passes through the aperture, and a compression seal stack is disposed within the aperture and around the optical fiber. The compression seal stack sealingly engages the optical fiber and the inner surface.

Abstract: An implantable medical device includes a control circuit for controlling the operation of the device and for obtaining physiological data from a patient in which the medical device is implanted. The implanted device also includes a communication circuit for transmitting the physiological data to an external device. A first power source is coupled to the control circuit and provides power to the control circuit. A second power source is coupled to the communication circuit and provides power to the communication circuit.

Abstract: A catheter is fabricated by joining a first catheter body segment, the first segment including a braided or coiled filament reinforcing layer contained within an outer layer, to a second catheter body segment by thermal fusion in a zone including an interface between the first segment and the second segment and at a temperature causing ends of the filament reinforcing layer in the zone to extend outward within the outer layer. Following thermal fusion, the extending ends of the filament reinforcing layer are removed.