Abstract: Alkylated interleukin-18 (IL-18), compositions comprising alkylated IL-18, kits comprising such compositions, methods of alkylating IL-18, and methods of using compositions comprising alkylated IL-18.
Type:
Grant
Filed:
December 21, 2009
Date of Patent:
May 1, 2012
Assignee:
Abbott Laboratories
Inventors:
Elaine Marie Brate, Tracey D. Rae, Cheng Zhao
Abstract: A method of assessing whether or not erythrocytes are suitable for transfusion into a recipient comprising (i) assaying a sample of erythrocytes for free choline, and (ii) comparing the level of free choline in the sample with the level of free choline deemed suitable for transfusion therapies; and a kit for use in such a method comprising at least one reagent for assaying the sample, instructions for conducting the assaying of the sample, and guidelines for assessing the suitability of the erythrocytes for transfusion.
Type:
Grant
Filed:
April 21, 2008
Date of Patent:
October 12, 2010
Assignee:
Abbott Laboratories
Inventors:
Maciej Adamczyk, Roy Jeffrey Brashear, Phillip G. Mattingly