Abstract: A method and apparatus for automatically detecting and diagnosing lead-related conditions is provided. Specifically, relatively short-term and relatively long-term impedance parameters are determined for detecting an impedance trend indicative of a lead-related condition such as an open circuit, which may be due to a conductor fracture or poor connection to an associated implantable medical device, or a short circuit due to an insulation breach. Monitoring of multiple lead impedance parameters is performed to diagnose a lead-related condition based on a number of diagnostic criteria. Supplementary analysis of multiple lead impedance parameter trends may be performed to identify lead-specific conditions, such as metal ion oxidation induced insulation degradation. A lead-related condition diagnosis and supporting data are stored in memory for uplinking to an external device for review by a clinician.

Abstract: An electrode assembly in embodiments of the invention can include a unitary member formed from an electrically conductive material having a central portion, and tab and plate portions extending radially outward from the central portion. The unitary member can be folded to configure the plate portions in a stacked configuration, thereby providing an electrically connected support structure for a cathode and/or anode assembly without individual connections/welds of plates to a common connection. The elimination of multiple welds lowers the internal resistance of the electrode assembly, and improves the structural integrity. Embodiments of the invention include batteries and implantable medical devices (IMDs) which incorporate the design flexibility in the shape and contour of the electrode assembly and hence, the overall shape and design of batteries and IMDs.

Abstract: A process for fabricating a medical assembly having a medical device at least a portion of which is formed of inorganic material is provided. The medical assembly is suitable for substantially long-term implantation in a host animal. The process includes modifying a surface of the medical device to form a hydrophilic adhesion-promoting surface. The hydrophilic adhesion-promoting surface is coated with an alginate solution comprising alginate and the alginate is reacted with alkaline earth metal cations.