Patents Represented by Attorney, Agent or Law Firm Caroline Nash
  • Therapeutic treatment and prevention of infections with a bioactive materials encapsulated within a biodegradable-biocompatible polymeric matrix
    Patent number: 6309669
    Abstract: Novel burst-free, sustained release biocompatible and biodegrable microcapsules which can be programmed to release their active core for variable durations ranging from 1-100 days in an aqueous physiological environment. The microcapsules are comprised of a core of polypeptide or other biologically active agent encapsulated in a matrix of poly(lactide/glycolide) copolymer, which may contain a pharmaceutically-acceptable adjuvant, as a blend of upcapped free carboxyl end group and end-capped forms ranging in ratios from 100/0 to 1/99.
    Type: Grant
    Filed: January 27, 1997
    Date of Patent: October 30, 2001
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Jean A. Setterstrom, John E. Van Hamont, Robert H. Reid, Elliot Jacob, Ramasubbu Jeyanthi, Edgar C. Boedeker, Charles E. McQueen, Daniel L. Jarboe, Frederick Cassels, William Brown, Curt Thies, Thomas R. Tice, F. Donald Roberts, Phil Friden