Abstract: The present invention relates to methods and compositions for the diagnosis and treatment of sepsis. The present invention also provides methods of providing a prognosis to a patient with sepsis. In particular, the present invention relates to compositions and methods for the detection of C5aR expression and the correlation of C5aR expression level with prognosis in sepsis.
Type:
Grant
Filed:
November 5, 2003
Date of Patent:
November 25, 2008
Assignee:
The Regents of the University of Michigan
Inventors:
Renfeng Guo, Niels C. Riedemann, Peter A. Ward, Markus Huber-Lang, J. Vidya Sarma