Abstract: A component, especially a hot gas component of a turbomachine, has at least one passage (7, 7?), especially a cooling passage, which is embedded in an outer wall (5) of the component (1) of the turbomachine and basically extends parallel to the surface (6) of the component (1). The component (1) has a basic body (8) and at least one coating (9) which is applied to the basic body on the outside, and the passage (7, 7?) on one hand is formed by a cavity which is formed in the basic body (8), and on the other hand is closed off towards the surface (6) of the component (1) by the coating (9).
Abstract: In a method for adjusting a Helmholtz resonator (10), in which a resonator volume (11) is connected to a space (13) to be provided with damping along an axis (29) via a constriction (12) having an acoustic impedance, the acoustic impedance of the constriction (12) is altered in order to adjust the Helmholtz resonator (10).
Abstract: An L-amino acid is produced by culturing a bacterium belonging to the family Enterobacteriaceae, which has an L-amino acid-producing ability and inherently has a native activity of a glucose dehydrogenase that uses pyrroloquinoline quinone as a coenzyme, but has been modified so that the activity of the glucose dehydrogenase is reduced, in a medium, and collecting the L-amino acid from the medium.
Type:
Grant
Filed:
March 1, 2011
Date of Patent:
June 26, 2012
Assignee:
Ajinomoto Co., Inc.
Inventors:
Rie Takikawa, Yoshihiko Hara, Gen Nonaka, Kazuhiro Takumi
Abstract: This present invention provides crystallization of ?-form crystals preferentially which are metastable crystals without precipitating ?-form crystals. This method allows for the precipitation of ?-form crystals which are metastable crystals by combining (a) the process of achieving supersaturation by mixing an acidic solution with an aqueous solution containing glutamic acid to attain a pH at the isoelectric point of glutamic acid or lower, and (b) after a certain elapsed time, adding more of the aqueous glutamic acid solution to achieve a second supersaturation.
Abstract: A method for producing a basic substance by fermentation comprising culturing a microorganism having an ability to produce the basic substance in a liquid medium contained in a fermentation tank to produce and accumulate the basic substance in the medium, wherein amount of sulfate and/or chloride ions used as counter ions of the basic substance is reduced by adjusting total ammonia concentration in the medium to be within a specific concentration range during at least a part of the total period of culture process.
Abstract: Isolated monoclonal antibodies or an antigen binding portion thereof which bind to prostate specific membrane antigen in its native form occurring on the surface of tumor cells characterized in that it is linked to a label or a cytotoxic agent or constructed as a part of a bispecific antibody or a recombinant diabody.
Type:
Grant
Filed:
March 2, 2006
Date of Patent:
June 12, 2012
Assignee:
Universitaetsklinikum Freiburg
Inventors:
Ursula Elsässer-Beile, Philipp Wolf, Dorothee Gierschner, Patrick Bühler, Ulrich Wetterauer
Abstract: A bacterium is described which belongs to the Enterobacteriaceae family, and has an ability to produce an L-amino acid, such as L-glutamic acid, L-arginine and L-threonine. The bacterium is modified so that the activity of a protein encoded by ydcI gene is decreased, thereby producing and accumulating the L-amino acid selected from L-glutamic acid, L-arginine, and L-threonine in the culture medium or cells of the bacterium when cultured in a culture medium. Subsequently, the L-amino acid is collected from the culture medium or the bacterium.
Abstract: A pair of pads is held against the remus of a patient's jaw, to prevent the jaw from slipping back and causing an airway obstruction, while the patient's neck is hyperextended to also cause the patient's airway to stay open. A device including the adjustable jaw pads as well as a triangularly shaped portion over which the patient's neck rests is not required to be attached to the surface on which the patient is lying, and permits the patient to be rolled on either side while still maintaining the patency of the patient's airway.
Abstract: The ability and speed with which a coryneform bacterium can produce L-lysine are improved when the coryneform bacterium contains an aspartokinase in which feedback inhibition by L-lysine and L-threonine is substantially desensitized. This is accomplished by successively enhancing the DNA coding for dihydrodipicolinate reductase, the DNA coding for dihydrodipicolinate synthase, the DNA coding for diaminopimelate decarboxylase, and the DNA coding for diaminopimelate dehydrogenase.
Abstract: A turbomachine (1), in particular a gas turbine, has a stator (2) and a rotor (3) and with at least one axial sealing device (6) arranged between them. On the stator side, the sealing device (6) has a radially stepped sealing contour (8) with regions (9, 10) projecting and retracting in the direction of the rotor (3), on the rotor side a plurality of sealing fins (11) projecting in the direction of the stator (2) being arranged, which engage in each case into adjacent retracting regions (10) of the stator-side sealing contour (8). On the rotor side, at least one additional fin (12) projecting in the direction of the stator (2) is provided, which is positioned between two adjacent sealing fins (11) arranged on the rotor side and which lies opposite a projecting region of the stator-side sealing contour (8).
Abstract: A method is described for producing an L-amino acid or a nucleic acid by culturing a microorganism having an ability to produce the L-amino acid or nucleic acid in a liquid medium in a fermentation tank containing a stirring impeller, and optionally adding seed crystals to the medium as required to produce and accumulate crystals of the L-amino acid or nucleic acid in the medium, and collecting crystals of the L-amino acid or nucleic acid from the culture. The power density of the stirring impeller is controlled to be 2.4 kW/m3 or lower after either precipitation of the crystals or addition of the seed crystals.
Abstract: The present invention encompasses a method for screening for a kokumi-imparting substance by using the calcium receptor activity as an index, a composition containing a kokumi-imparting substance obtained by the screening method, a method for producing food or drink imparted with kokumi, and food or drink imparted with kokumi.
Abstract: In a magnetron sputtering apparatus an arrangement is made such that the peripheral portion of a target is uniformly eroded to attain a high efficiency in target utilization and, in addition, that an abnormal discharging hardly occurs to thereby enable satisfactory thin film forming. A magnet assembly is provided behind a target that is disposed opposite to the process substrate. This magnet assembly has a central magnet that is disposed linearly along the longitudinal direction, and a peripheral magnet that is disposed so as to enclose the periphery of the central magnet, while changing the polarity on the side of the target. At this time, among the respective magnetic fluxes generated between the central magnet and the peripheral magnet at the longitudinally end portions of the magnet assembly, the position at which the vertical component of the magnetic field becomes zero is locally shifted to the central magnet within a certain range.
Abstract: An anterior lumbar interbody graft (ALIG) inserter includes prongs at the tip of the inserter which can optionally grasp, and thus insert, anterior and anterior-lateral grafts.
Abstract: A method for manufacturing a sheet-shaped body in which a powder particle layer is sandwiched between a base sheet to which a bonding agent is applied and a covering sheet so as to be bonded into an integral body, is provided with the steps of: shifting the base sheet, the powder particle layer and the covering sheet, with each of the sheets and the layer being held on the respective roller face, and after the powder particle layer has been transferred onto the base sheet, bonding the base sheet, the powder particle layer and the covering sheet into an integral form. Thus, the powder particle layer can be fixed to a predetermined position in a stable manner.