Abstract: The present invention includes an apparatus and method for holding a tool that includes one or more substantially cylindrical members, wherein each member has a longitudinal channel and a base having one or more planarly spaced substantially cylindrical openings and a longitudinal slot extending along each substantially cylindrical opening, wherein each substantially cylindrical member is secured within one of the cylindrical openings and is free to rotatively engage one or more tools.

Abstract: The present invention includes compositions and methods for increasing the effectiveness of antigen presentation using a DCIR-specific antibody or fragment thereof to which an antigen is attached that forms an antibody-antigen complex, wherein the antigen is processed and presented by a dendritic cell that has been contacted with the antibody-antigen complex.

Abstract: An apparatus and method for automatically focusing a lens of a digital imaging device, such as a digital still or video camera or camera phone, that reduces the auto focus time while not compromising image sharpness quality and simultaneously reducing device power consumption due to focus actuator movement, all without tuning or adjustment of thresholds or parameters is disclosed. The present invention automatically computes a set of digital band-pass filters matched to the imaging device specifications along with corresponding step-size magnitudes. A filter-switching search for the in-focus focus actuator position is formulated such that filters are switched and step-sizes are reduced as the search gets closer to the in-focus position by utilizing local estimates of the first and second-order differential information of the focus value surface.

Abstract: The present invention includes compositions and methods of treating a hydrocarbon-bearing formation, the formation having at least one fracture, by contacting the fracture with a composition that includes a solvent and a nonionic fluorinated polymeric surfactant, wherein the composition interacts with at least a portion of the proppants in the fracture.

Abstract: The present invention provides a CPR sensor that includes a thin and substantially flat flexible substrate having one or more sensor arrays, a power source, an output interface and a processor or analog circuit, all of which are disposed on the substantially flat flexible substrate. The substrate can be any shape (e.g., rectangular, circular, a polygon, an irregular shape that is decorative) and made from a polymer, metal film or other suitable material. Note that the substrate can be rigid or semi-flexible instead of flexible. A protective layer may cover the sensor array, the power source, and the processor or analog circuit. Alternatively, a protective covering can be used to encapsulate the device. The one or more sensor arrays measure one or more of the following compressions characteristics: compression depth, compression force, compression frequency and compression acceleration.

Abstract: The present invention includes methods of treatment and compositions for treating diseases related to the activity of a histone deacetylase in a subject by administering to the subject an effective amount of a modified FK228 compound comprising an amino acid conjugate which constitutes an amino thiol, a hydroxy thiol, a dithiol, or a hydroxamic acid, instead of a hydroxy-mercapto-heptenoic acid moiety in FK228.

Abstract: The present invention includes methods and compositions for liquid separation and water purification. The present invention includes a purification membrane having a polymer matrix purification membrane that has been treated with dopamine to form a polydopamine coated membrane with a high water flux and a high hydrophilicity.

Abstract: The present invention concerns a Ce-base amorphous metallic plastics being CeaAlbMc, in which 55?a?75, 5?b?25, 10?c?25, and a+b+c=100; said M is Co, Cu or Ni. Otherwise the metallic plastics could be CedAleCufZg, in which 55?d?75, 5?e?15, 15?f?25, 0.01?g?10, and d+e+f+g=100; said Z is one element selected from Co, Fe, Hf, Mg, Mo, Nb, Sc, Ta, Ti, W, Zn and Zr. The metallic plastic could also be CehAliCujNik, in which 55?h?75, 5?i?15, 15?j?25, 0.01?k<5, and h+i+j+k=100. The Ce-base amorphous metallic plastic has a low glass-transition temperature and a wide super-cooling liquid phase area, therefore possesses a high thermal stability. The material could be deformed, shaped and imprinting worked into desired amorphous alloy articles as thermoplastic plastics at a very low temperature.

Abstract: The present invention provides a system, method and apparatus that includes a user device having a magnetic field generator disposed within a substrate that is normally inactive, a biometric sensor mounted on the substrate, a memory disposed within the substrate and a processor disposed within the substrate that is communicably coupled to the magnetic field generator, the biometric sensor and the memory. The processor is operable to process biometric information received from the biometric sensor to verify that a user is authorized to use the apparatus and activate the magnetic field generator when the user is verified. A power source is also disposed within the substrate. The magnetic field generator can create a spatially varying magnetic signal using a magnetic stripe and one or more induction coils, or create a time-varying magnetic signal for emulating data obtained from swiping a magnetic stripe card through a magnetic card reader.

Abstract: The present invention includes a system, methods and apparatus for sterilization of an object (e.g., food products). The present invention takes advantage of the electron scatter that occurs when electron beam is applied onto a surface. The present invention is capable of treating irregular surfaces (e.g., carcasses, spherical/round surfaces) or any type of surface where complete penetration is not needed or desired.

Abstract: A method for treating a liquid is disclosed using an apparatus having: (a) a pump volute or hydrocyclone, (b) a throat connected to the pump volute or hydrocyclone head, (c) a parabolic reflector having a vertex, a focus and an opening at the vertex, wherein the opening is connected to the throat such that the vertex and focus are axially aligned with the central axis and the focus is not located within the throat, and (d) a wave energy source having a first electrode within the pump volute or hydrocyclone head that extends into the throat along the central axis of the throat, and a second electrode extending into the parabolic reflector proximate to the focus wherein the second electrode is spaced apart and axially aligned with first electrode. The liquid is supplied to the pump volute or hydrocyclone head and is irradiated by the wave energy source.

Abstract: The present invention provides a performance assay that measures the total antioxidant activity of a composition using oxygen uptake in contrast to prior art methods that measure antioxidant capacity by indirectly measuring degradation of a fluorescent compound by following the disappearance of fluorescence. Using the performance antioxidant assay of the present invention, an antioxidant composition having synergistic activity is provided by the present inventors that includes flavonoids such as the flavonol quercetin, mixed tocopherols or tocotrienols, grape skin extract, green tea extract and bush plum. The antioxidant activity of the present composition exceeds 6,000 micromoles Trolox equivalent units per gram using the present invention.

Abstract: Novel antigen-presenting cells, including but not limited to dendritic cells, that are loaded with antigens from dead or dying cells including allogenic cell lines, and the methods for making such antigen-presenting cells are described. These loaded antigen-presenting cells induce therapeutic immune responses in humans. Such loaded antigen-presenting cells are useful in the management of cancer. Antigen-loaded dendritic cells prepared as described here can prime naïve T cells to differentiate into effector cells able to recognize multiple and/or shared tumor antigens that are expressed either on the tumor cells that are used to load the dendritic cells and/or on other tumor cells. The cytotoxic T cells generated by exposure to antigen-loaded dendritic cells prepared as described here can be used in adoptive therapy. This induction of responses against multiple antigens shared between different cells, for instance tumor cells, as described here is important as it leads to broad immune responses.

Abstract: A method and apparatus for treating a fluid using a wave energy uses a cyclone separator configured to create a flow of the fluid in a thin film along a vortex path from a first end to a second end of the cyclone separator, a first electrode and a second electrode that are at least partially disposed within the cyclone separator, spaced apart from one another, and axially aligned with one another along a central axis of the cyclone separator from the first end to the second end. The electrodes are used to create an open electrical arc to provide the wave energy directly exposing the fluid as the fluid flows along the vortex path in close proximity to and surrounding the electrical arc such that only a gas separates the fluid from the open electrical arc.

Abstract: The present invention includes programs, devices and methods for a programmable ball throwing machine that is able to eject balls to preset, programmed or manually-selected positions with programmable projection and travel characteristics. The present invention includes a computer implemented method for controlling the parameters of a ball flight and trajectory in three dimensions including one or more parameters to identify a flight and trajectory of a ball in three dimensions for one or more player positions and a processor to control one or more motors in response to the one or more parameters.

Abstract: The present invention provides a compositions and methods for the treatment of cancer, including pancreatic cancer, breast cancer and melanoma, in a human patient. The methods and compositions of the present invention employ curcumin or a curcumin analogue encapsulated in a colloidal drug delivery system, preferably a liposomal drug delivery system. Suitable colloidal drug delivery systems also include nanoparticles, nanocapsules, microparticles or block copolymer micelles. The colloidal drug delivery system encapsulating curcumin or a curcumin analogue is administered parenterally in a pharmaceutically acceptable carrier.

Abstract: The present invention provides a system and method for producing hot water without a flame. The system and method heats water to at least a specified temperature without a flame by providing a source of water and a prime mover, pumping water from the source of water into one or more heat exchangers, pre-heating the water using the one or more heat exchangers, heating the pre-heated water to at least the specified temperature without a flame using a dynamic heat generator driven by the prime mover, using the heated water in the one or more heat exchangers to pre-heat the water and providing the heated water to an output.

Abstract: An apparatus and method to determine fractions of various phases in a multiphase fluid. The apparatus includes main body including an interior configured receive a multiphase fluid and an exterior. The apparatus senses fluid pressure of multiphase fluid received in the interior and senses a fluid temperature of the multiphase fluid. The apparatus transmits an ultrasonic wave into the fluid and detects the transmitted wave to determine its velocity and attenuation. The apparatus may adjust the determined velocity and attenuation based on the temperature and pressure of the fluid to compensate for a difference between the sensed temperature and pressure and a standard temperature and pressure. The apparatus determines a gas fraction, water fraction, and a non-water fluid fraction of the multiphase fluid based on the sensed fluid pressure, the sensed fluid temperature, and the velocity and attenuation of the ultrasonic wave in the multiphase fluid.

Abstract: The present invention includes a microscope and a method for using the microscope for single molecule with reduced photobleaching of a fluorophore (20) that includes a light translucent material (16); a metal layer (18) disposed on the light translucent material (16); a medium (15) disposed on the metal layer (18), the medium (15) having one or more fluorophores (20) capable of binding a target analyte (e.g.