Patents Represented by Attorney Charles C. Caruso

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  • Process for preparing an antihypercalcemic agent
    Patent number: 5159108
    Abstract: Described is a new process for producing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP), a new antihypercalcemic agent. The process involves a 3-step sequence starting with 4-phthalimidobutanoyl chloride which can be practiced as a "one-pot" reaction sequence, without employing PCl.sub.3 or H.sub.3 PO.sub.3.
    Type: Grant
    Filed: August 1, 1991
    Date of Patent: October 27, 1992
    Assignee: Merck & Co., Inc.
    Inventor: Gerard R. Kieczykowski