Patents Represented by Attorney, Agent or Law Firm Charles E. Cohen
  • SAM operon
    Patent number: 6312920
    Abstract: The invention provides isolated nucleic acid compounds encoding a novel SAM synthetase of Streptomyces fradiae. Also provided are vectors and transformed heterologous host cells for expressing the SAM synthetase and a method for preparing S-adenosylmethionine from recombinant host cells transformed with the SAM synthetase gene.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: November 6, 2001
    Assignee: Eli Lilly and Company
    Inventors: Bradley Stuart DeHoff, Paul Robert Rosteck, Jr.
  • Glucosyltransferase gene gtfe from Amycolatopsis orientalis
    Patent number: 6232102
    Abstract: The invention provides isolated nucleic acid compounds encoding a glycosyltransferase enzyme of Amycolatopsis orientalis. Also provided are vectors carrying genes that encode said enzyme, transformed heterologous host cells for expressing said enzyme, and methods for producing glycopeptide compounds using the cloned genes that encode said enzyme.
    Type: Grant
    Filed: November 23, 1998
    Date of Patent: May 15, 2001
    Assignee: Eli Lilly and Company
    Inventors: Richard H. Baltz, Patricia J. Solenberg, Patti J. Treadway
  • Streptococcus pneumoniae gene sequence dnaG
    Patent number: 6162617
    Abstract: The invention provides isolated nucleic acid compounds encoding dnaG of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: December 19, 2000
    Assignee: Eli Lilly and Company
    Inventors: Stanley Gene Burgett, Jo Ann Hoskins, Stanley Richard Jaskunas, Jr., Robert Brown Peery, Paul Robert Rosteck, Jr., Genshi Zhao
  • Monofunctional glycosyltransferase of Staphylococcus aureus
    Patent number: 6143868
    Abstract: The invention provides isolated nucleic acid compounds encoding a novel MTG of Staphylococcus aureus. Also provided are vectors and transformed heterologous host cells for expressing the MTG and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the MTG.
    Type: Grant
    Filed: April 9, 1998
    Date of Patent: November 7, 2000
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Stanley R. Jaskunas, Jr., Robert B. Peery, Paul L. Skatrud
  • Strepococcus pneumoniae gene sequence FtsH
    Patent number: 6136557
    Abstract: The invention provides isolated nucleic acid compounds encoding FtsH of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: October 24, 2000
    Assignee: Eli Lilly and Company
    Inventors: Robert Brown Peery, Paul Luther Skatrud, Q May Wang, Michele Louise Young Bellido
  • Multiple drug resistance gene atrc of Aspergillus nidulans
    Patent number: 6060264
    Abstract: The invention provides isolated nucleic acid compounds encoding a multiple drug resistance protein of Aspergillus nidulans. Vectors and transformed host cells comprising the multiple drug resistance-encoding DNA of Aspergillus nidulans atrC are also provided. The invention further provides assays which utilize these transformed host cells.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: May 9, 2000
    Assignee: Eli Lilly and Company
    Inventors: Paul Luther Skatrud, Maarten A. de Waard, Alan C. Andrade, Robert Brown Peery