Abstract: The invention provides antiviral therapeutic methods employing bovine or ovine interferon-tau (IFN-.tau.) proteins and polypeptides. The IFN-.tau. proteins exhibit the antiviral and antiproliferative properties characteristic of type I interferons. An advantage of the invention is that IFN-.tau. has essentially no cytotoxic effects on treated cells as does, for example, IFN-.alpha..
Type:
Grant
Filed:
May 31, 1995
Date of Patent:
August 24, 1999
Assignee:
University of Florida
Inventors:
Fuller Warren Bazer, Howard Marcellus Johnson, Carol Hanlon Pontzer, Troy Lee Ott, Gino Van Heeke