Abstract: Using the nontoxic heavy chain fragment from botulinum neurotoxins A-G, compositions and methods of use in inducing an immune response which is protective against intoxication with botulinum in subjects is described.
Type:
Grant
Filed:
July 9, 1999
Date of Patent:
December 17, 2002
Assignee:
The United States of America as represented by the Secretary
of the Army
Inventors:
John S. Lee, Peter Pushko, Jonathan F. Smith, Michael Parker, Mark T. Dertzbaugh, Leonard Smith