Patents Represented by Attorney, Agent or Law Firm Charles M. Kinig
  • Polynucleotide sequences of human EDG-1c
    Patent number: 6423508
    Abstract: Human EDG-1c polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Human EDG-1c is identified as a selective receptor for sphingosine-1-phosphate (“S-1-P”) and for di-hydro S-1-P. Also diclsosed are methods for discovering agonists and antagonists of the interaction between S-1-P and di-hydro S-1-P and their cellular receptor, human EDG-1c, which may have utility in the treatment of several human diseases and disorders.
    Type: Grant
    Filed: March 4, 1999
    Date of Patent: July 23, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham PLC, SB Laboratories Pharmaceutiques
    Inventors: Derk J. Bergsma, Winnie Chan, Nassirah Khandoudi, Phillipe Robert