Abstract: The present invention relates to novel phthalazine derivatives and, more particularly, to phthalazine derivatives of formula (III) that are useful as protein kinase inhibitors. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and methods of treatment using the compounds.
Type:
Grant
Filed:
November 14, 2007
Date of Patent:
October 25, 2011
Assignee:
Forest Laboratories Holdings Limited
Inventors:
Gian-Luca Araldi, Matthew Ronsheim, Melanie Ronsheim
Abstract: The present invention relates to pyridoazepine derivatives that act as 5-HT ligands, e.g., 5-HT2 C. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
Type:
Grant
Filed:
May 23, 2007
Date of Patent:
March 1, 2011
Assignee:
Forest Laboratories Holdings Limited
Inventors:
Gian-Luca Araldi, Alexander Bischoff, Nhut K. Diep
Abstract: The present invention relates to piperazine derivatives that act as inhibitors of stearoyl-CoA desaturase. The invention also relates to methods of preparing the compounds, compositions containing the compounds, and to methods of treatment using the compounds.
Abstract: Nebivolol has been shown to be beneficial in the treatment of cardiovascular diseases such hypertension, congestive heart failure, arterial stiffness and endothelial dysfunction. The present invention features a pharmaceutical composition comprising nebivolol and at least one other active agent, wherein the at least one other active agent is a cardiovascular agent.
Type:
Grant
Filed:
November 15, 2005
Date of Patent:
November 23, 2010
Assignee:
Forest Laboratories Holdings Limited
Inventors:
Eric Davis, John P. O'Donnell, Peter Bruce Bottini, Andrew Shaw, R. Preston Mason
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