Patents Represented by Attorney Charles W. Asbrook

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  • Substituted 1-sulfonylbenzimidazoles
    Patent number: 4243813
    Abstract: Certain 1-sulfonyl-2,5(6)-substituted-benzimidazole compounds are useful as antiviral agents.
    Type: Grant
    Filed: August 13, 1979
    Date of Patent: January 6, 1981
    Assignee: Eli Lilly and Company
    Inventors: Charles J. Paget, James H. Wikel
  • Process for producing 7-amino-7-alkoxycephalosporins
    Patent number: 4242509
    Abstract: A 7-(5-amino-5-carboxyvaleramido)-7-methoxycephalosporin with amino and acid groups protected is reacted with PCl.sub.5 or other agent capable of forming an imino halide; the resulting imino halide is thereafter reacted under essentially non-aqueous conditions with a primary loweralkanol of C.sub.1 -C.sub.4 or with methan-d.sub.3 -ol, yielding nucleus bearing a 7-alkoxy group derived from the primary loweralkanol or methan-d.sub.3 -ol. In situ acylation of the nucleus affords 7-acylamido-7-alkoxycephalosporins in good yield; these products can be deesterified to yield the corresponding acids, which exhibit antibacterial activity.
    Type: Grant
    Filed: April 13, 1979
    Date of Patent: December 30, 1980
    Assignee: Eli Lilly and Company
    Inventor: William H. W. Lunn
  • Alkylidenylmethyl-substituted 1-sulfonylbenzimidazoles
    Patent number: 4174454
    Abstract: Certain alkylidenylmethyl-substituted-1-sulfonylbenzimidazole compounds are useful as antiviral agents.
    Type: Grant
    Filed: March 3, 1978
    Date of Patent: November 13, 1979
    Assignee: Eli Lilly and Company
    Inventors: Charles J. Paget, James W. Chamberlin, James H. Wikel