Patents Represented by Attorney, Agent or Law Firm Cherskov & Flaynik
  • Patent number: 6610304
    Abstract: The incorporation of multiple branch peptide constructions having activity against HIV into liposomes of sufficient size for white blood cell internalization (e.g. greater than 150 nm and preferably approximately 250-400 nm. ) has been shown to increase the activity of those MBPCs manifold. The liposomes and pharmaceutical compositions are described herein.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: August 26, 2003
    Inventor: Bonabes-Olivier de Rougé
  • Patent number: 6601675
    Abstract: A folding and self-locking sawhorse comprised of two frames connected by the tops (20) and the middle horizontal brace (24) to create a combination of two opposing forces which product a rigid sawhorse in the open position, but remains collapsible and folds for storage when the two forces are not in opposition. The sawhorse has a clamping top (20) top which can hold items with a compression force created by the expansion force induced by a folding hinged lever (26) against the two side frames. The clamping top (20) accepts tabletops (42) and other items (46) and the locking divergence of the legs (22) can be used to mate the sawhorse with a base (34) for better stability. An alternative embodiment of the locking foldable sawhorse (58) includes one or more beams (57) set upon a beam support structure (57a).
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: August 5, 2003
    Inventor: Donald P. Gulledge
  • Patent number: 6572519
    Abstract: The invention is a creasing device for creasing paper or card before it is folded. The device consists of a drum-shaped male component (2) featuring grooves (8, 10, 12) of various widths and depths to hold rubber O-rings (24, 26, 28). A female component (4) is almost identical to the male component (2) but has receiving grooves (14, 16, 18) that are slightly wider and deeper. When fixed to top and bottom shafts with one O-ring (24, 26, 28) in a groove (8, 10, 12) on the male component (2) aligned with a receiving groove (14, 16, 18) of the female component (4), a sheet of paper fed between the drums will be creased by the pressure of the O-ring (24, 26, 28) forcing the paper into the receiving groove (14, 16, 18). The invention allows the device to be quickly and easily set up to form creases of various widths and depths, while the resilient O-rings minimize damage to the paper.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: June 3, 2003
    Inventor: Graham Harris
  • Patent number: 6543390
    Abstract: An attachment to a typical commercial animal chest harness comprises a rear harness defining two leg loops adapted to receive the animal's hind legs, a strap or other such flexible attachment for connecting the rear harness to a first fixed point, a strap for joining the rear harness to the chest harness, and another strap or other such flexible attachment connecting the chest harness to a second fixed point.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: April 8, 2003
    Inventor: Lisa Lowery
  • Patent number: 6543644
    Abstract: A container (11) for a liquid containing bag. The container is capable of adjusting the flow rate of a liquid (41) to be poured out. The container includes a container body (12) having an opening (24), and a cap (13) for selectively closing the opening. The container body is closed by a pair of lids (17). The upper end portion of the bag (42) is supported between mating faces (25) of the lids. The cap has fasteners (37) for clamping the upper end portion of the bag. When the cap is slid along grooves (26) formed in the lids, the fasteners close a pourer (43) of the bag.
    Type: Grant
    Filed: December 5, 2000
    Date of Patent: April 8, 2003
    Assignee: Kabushiki Kaisha Makino Sogo Kenkyujo
    Inventors: Hideya Makino, Yutaka Iwashita
  • Patent number: 6537575
    Abstract: A mixture is provided which manifests a gel phase at a temperature higher than that in which the mixture manifests a liquid phase. The mixture is a combination of a lipid, a polymer-grafted phospholipid and a surfactant. It is biomimetic in nature and changes phases when subjected to one or a plurality of environmental stimuli.
    Type: Grant
    Filed: July 28, 2000
    Date of Patent: March 25, 2003
    Assignee: The University of Chicago
    Inventors: Millicent A. Firestone, David M. Tiede
  • Patent number: 6533821
    Abstract: The invention provides for a bio-adhesive derived from a mixture comprising KH2PO4, a metal oxide, a calcium-containing compound, and water. Also provided is a reabsorbable bone substitute derived from a mixture comprising KH2PO4 and an oxide in a 1:1 weight percent ratio, a calcium-containing compound, and water.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: March 18, 2003
    Inventor: Thomas Lally
  • Patent number: 6499330
    Abstract: A displacement indicator device 10 for a press brake compensator 16 includes a first recess 20 in a lower wall of a preselected portion or a die holder member 14 of the press brake compensator 16, an indicator rod 18 snugly inserted into the first recess 20, a second recess 34 in a side wall 36 of a preselected portion of a wedge portion 38 of the press brake compensator 16, and a lifting cam 40 snugly inserted into the second recess 34. The indicator rod 18 is displaced by the movement of the preselected portion of the wedge portion 38. The indicator rod 18 displacement corresponds to the vertical displacement of the die holder member 14. An indicating scale 32 discloses the amount of displacement of the preselected portion of the die holder member 14 by aligning a reference mark 28 on the indicator rod 18 with a horizontal line and corresponding number on the indicating scale 32.
    Type: Grant
    Filed: September 11, 2000
    Date of Patent: December 31, 2002
    Inventor: Bruno J. Pelech, Jr.
  • Patent number: 6498119
    Abstract: A new method for combining elemental iron and other metals to form an inexpensive ceramic to stabilize arsenic, alkaline red mud wastes, swarfs, and other iron or metal-based additives, to create products and waste forms which can be poured or dye cast.
    Type: Grant
    Filed: December 29, 2000
    Date of Patent: December 24, 2002
    Assignee: University of Chicago
    Inventors: Arun S. Wagh, Seung-Young Jeong
  • Patent number: 6495014
    Abstract: A porous immobilized ion-exchange material is provided. Also provided is an electrodeionization device incorporating the material. A method for subjecting a fluid to electrodeionization, is provided utilizing porous immobilized ion-exchange material. A salient feature of the material is that it can be regenerated in situ.
    Type: Grant
    Filed: July 12, 2001
    Date of Patent: December 17, 2002
    Assignee: University of Chicago
    Inventors: Rathin Datta, YuPo Lin, Dennis Burke, Shih-Perng Tsai
  • Patent number: 6494075
    Abstract: A device 10 for securing a punch 13 to a press brake 44 includes a first member 12 removably inserted into an aperture 32 in the punch 13, a second member 14 integrally joined to the first member 12, a set screw 18 extending through the first and second members 12 and 14 to ultimately engage a wall 64 of the aperture 32 to maintain the horizontal position of the first and second members 12 and 14 relative to the punch 13, an extension portion 36 of the second member 14 that ultimately engages a cooperating portion 42 of the press brake 44, and a lip portion 46 that horizontally positions the extension portion 36 adjacent to a top wall 26 of the punch 13 thereby promoting accurate engagement with the cooperating portion 42 of the press brake 44.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: December 17, 2002
    Inventor: Bruno J. Pelech, Jr.
  • Patent number: 6485541
    Abstract: A method to minimize oxidation of metal during melting processes is provided, the method comprising placing solid phase metal into a furnace environ-ment, transforming the solid-phase metal into molten metal phase having a molten metal surface, and creating a barrier between the surface and the environment. Also provided is a method for isolating the surface of molten metal from its environment, the method comprising confining the molten metal to a controlled atmos-phere, and imposing a floating substrate between the surface and the atmosphere.
    Type: Grant
    Filed: August 4, 2000
    Date of Patent: November 26, 2002
    Assignee: The University of Chicago
    Inventors: John N. Hryn, Michael J. Pellin, Wallis F. Calaway, Jr., Jerry F. Moore, Gregory K. Krumdick
  • Patent number: 6465174
    Abstract: A method for determining the existence of duplexes of oligonucleotide complementary molecules is provided whereby a plurality of immobilized oligonucleotide molecules, each of a specific length and each having a specific base sequence, is contacted with complementary, single stranded oligonucleotide molecules to form a duplex so as to facilitate intercalation of a fluorescent dye between the base planes of the duplex. The invention also provides for a method for constructing oligonucleotide matrices comprising confining light sensitive fluid to a surface, exposing said light-sensitive fluid to a light pattern so as to cause the fluid exposed to the light to polymerize into discrete units and adhere to the surface; and contacting each of the units with a set of different oligonucleotide molecules so as to allow the molecules to disperse into the units.
    Type: Grant
    Filed: July 31, 1998
    Date of Patent: October 15, 2002
    Assignee: University of Chicago
    Inventors: Andrei Darievich Mirzabekov, Gennadiy Moiseyevich Yershov, Dmitry Yuryevich Guschin, Margaret Anne Gemmell, Valentine V. Shick, Dmitri Y. Proudnikov, Edward N. Timofeev
  • Patent number: 6465216
    Abstract: A method for expressing and purifying foreign proteins in photosynthetic organisms comprising the simultaneous expression of both the heterologous protein and a means for compartmentalizing or sequestering of the protein.
    Type: Grant
    Filed: February 1, 2001
    Date of Patent: October 15, 2002
    Assignee: University of Chicago
    Inventors: Philip D. Laible, Deborah K. Hanson
  • Patent number: 6464880
    Abstract: A method is provided for producing porous hydrophilic materials whereby nonporous materials are subjected to ester hydrolysis to generate site-specific perforations. Processes for separating aqueous phase from organic and aqueous mixtures utilizing the invented materials also are provided.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: October 15, 2002
    Assignee: University of Chicago
    Inventors: Rathin Datta, Shih-Perng Tsai, Michael P. Henry
  • Patent number: 6440671
    Abstract: A method for detecting disease-associated alleles in patient genetic material is provided whereby a first group of oligonucleotide molecules, synthesized to compliment base sequences of the disease associated alleles is immobilized on a predetermined position on a substrate, and then contacted with patient genetic material to form duplexes. The duplexes are then contacted with a second group of oligonucleotide molecules which are synthesized to extend the predetermined length of the oligonucleotide molecules of the first group, and where each of the oligonucleotide molecules of the second group are tagged and either incorporate universal bases or a mixture of guanine, cytosine, thymine, and adenine, or complementary nucleotide strands that are tagged with a different fluorochrome which radiates light at a predetermined wavelength.
    Type: Grant
    Filed: February 7, 2000
    Date of Patent: August 27, 2002
    Assignee: The University of Chicago
    Inventors: Andrei Darievich Mirzabekov, Eugene Vladislavovich Kirillov, Sergei Valeryevich Parinov, Victor Evgenievich Barski, Svetlana Alekseevna Dubiley
  • Patent number: 6429750
    Abstract: An EMI attenuation device comprising at least two substrates such that the spacing between these substrates is selected to maximize shielding performance at a particular frequency. The device further comprises additional substrates arranged at predetermined distances from the first two substrates to optimize shielding performance. A method also is provided for a multistep, attenuation of impinging EMI, wherein the method also enables see-through and/or hear-through monitoring. Salient features of the method include relatively positioning a plurality of electrically conductive substrates, each of a particular topology, so as to maximize attenuation of the EMI at particular frequencies.
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: August 6, 2002
    Assignee: The Curran Company
    Inventors: William E. Curran, Sr., Michael T. Egan, Joseph C. Weibler
  • Patent number: 6405389
    Abstract: A versatile, compact, rapidly deployable and easily disposable contamination device that can accommodate various regions of the human body in isolation is provided. The device is deployable in a few seconds; isolates a patient's body region; accommodates any of the extremities of the human body, as well as the head and limbs, while minimizing the patient's discomfort; allows for the drainage and storage of contaminants and body fluids; and is easily disposable as a whole in a container provided for that purpose. Portions of the device are re-usable while other portions of the device are utilized to store contaminating fluid.
    Type: Grant
    Filed: December 7, 1999
    Date of Patent: June 18, 2002
    Inventor: Robert D. Harty
  • Patent number: 6405586
    Abstract: An improved roller 12 for a dynamometer 10 includes a plurality of equally spaced, congruent recesses 16 parallel to the longitudinal axis of the roller 12 and circumferentially positioned around the perimeter of the roller 12. The recesses 16 form a plurality of equally spaced, substantially planar, congruent surfaces 18 parallel to the longitudinal axis of the roller 12 and circumferentially positioned around the perimeter of the roller 12. The surfaces 18 engage the drive wheel of a vehicle and limit slippage and/or creepage between the drive wheel and the roller resulting in increased power transfer between the drive wheel and roller and increased dynamometer accuracy and repeatability.
    Type: Grant
    Filed: January 31, 2000
    Date of Patent: June 18, 2002
    Inventor: Marc W. Salvisberg
  • Patent number: 6403018
    Abstract: A method for producing composite ceramic material is provided wherein a core ceramic structure is produced and simultaneously enveloped with a sleeve of similar material.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: June 11, 2002
    Assignee: The University of Chicago
    Inventors: Kenneth C. Goretta, Dileep Singh, Bryant J. Polzin, Terry Cruse, John J. Picciolo