Abstract: The present invention relates to rapid, reliable and effective assays for screening and identifying pharmaceutically effective compounds that specifically inhibit the biological activity of fungal GTPase proteins, particularly GTPases involved in cell wall integrity, hyphael formation, and/or other cellular functions critical to pathogenesis.

Abstract: A motion sensitive theft detector system for portable articles featuring two way communication between the theft detector unit installed in or affixed to the portable article and the control unit carried by the owner. The theft detector communicates alerts to the control unit allowing the user to screen for false alarms and to trigger an alarm at the portable article when warranted. A second alarm function selected by the mode switch sounds an alarm automatically in response to motion according to an adaptive alarm sequence. The adaptive alarm varies the alarm in response to frequency and duration of motion so that isolated movement triggers a warning but persistent motion triggers a full scale alarm.