Patents Represented by Law Firm Christenssen, O'Connor, Johnson & Kindness PLLC
  • Urinary assay for measuring bone resorption
    Patent number: 5945274
    Abstract: A method for assaying bone resorption rates which consists of quantitating the concentration of free lysyl pyridinoline derived from bone collagen, found in a body fluid is disclosed. The method includes immunometric assay, fluorometric assay and electrochemical titration. The structure of specific 3-hydroxypyridinium cross-links found in urine of Paget's disease patients and procedures for making monoclonal antibodies is described.
    Type: Grant
    Filed: March 24, 1998
    Date of Patent: August 31, 1999
    Assignee: Washington Research Foundation
    Inventor: David R. Eyre