Abstract: The present invention relates generally to immunization methods using recombinant viral vectors. In particular, the invention relates to methods and compositions for immunizing a subject with a nucleic acid molecule encoding an antigen of interest, wherein the nucleic acid molecule is delivered to the subject via a recombinant AAV virion.
Type:
Grant
Filed:
July 23, 1998
Date of Patent:
June 5, 2001
Assignee:
Avigen, Inc.
Inventors:
Gary J. Kurtzman, Edgar G. Engelman, Greg M. Podsakoff, Dirk G. Brockstedt