Patents Represented by Attorney, Agent or Law Firm Christine F. Martin
  • Peptide substrates for HCV NS3 protease assays
    Patent number: 6251583
    Abstract: Novel chromogenic, fluorogenic and fluorescence polarization substrates which are useful in HCV NS3 protease and inhibitor assays.
    Type: Grant
    Filed: April 8, 1999
    Date of Patent: June 26, 2001
    Assignee: Schering Corporation
    Inventors: Rumin Zhang, Bruce A. Malcolm, Brian M. Beyer, F. George Njoroge, James P. Durkin, William T. Windsor
  • Single-chain recombinant complexes of hepatitis C virus NS3 protease and NS4A cofactor peptide
    Patent number: 6211338
    Abstract: Covalent HCV NS4A-NS3 complexes comprising the central hydrophobic domain of native HCV NS4A peptide, a linker, and the HCV NS3 serine protease domain, wherein the hydrophobic domain of native HCV NS4A peptide is tethered by the linker to the amino terminus of the HCV NS3 protease domain.
    Type: Grant
    Filed: November 24, 1998
    Date of Patent: April 3, 2001
    Assignee: Schering Corporation
    Inventors: Bruce A. Malcolm, S. Shane Taremi, Patricia C. Weber, Nanhua Yao