Patents Represented by Attorney, Agent or Law Firm Christopher A. Hare
  • Human monoclonal antibodies to epidermal growth factor receptor
    Patent number: 6235883
    Abstract: In accordance with the present invention, there are provided fully human monoclonal antibodies against human epidermal growth factor receptor (EGF-r). Nucelotide sequences encoding and amino acid sequences comprising heavy and light chain immunoglobulin molecules, particularly sequences corresponding to contiguous heavy and light chain sequences from CDR1 through CDR3, are provided. Hybridomas expressing such immunoglobulin molecules and monoclonal antibodies are also provided.
    Type: Grant
    Filed: May 5, 1997
    Date of Patent: May 22, 2001
    Assignee: Abgenix, Inc.
    Inventors: Aya Jakobovits, Xiao-Dong Yang, Michael Gallo, Xiao-Chi Jia