Abstract: A stabilizer composition, useful for reduced fat frozen desserts and whipped toppings, containing, as a first component, microcrystalline cellulose coprocessed with guar and, as a second component, microcrystalline cellulose coprocessed with carboxymethylcellulose. The method of using the stabilizer composition provides reduced fat food products, particularly products with less than ten percent fat, with many of the desirable body and textural characteristics of full-fat products.
Type:
Grant
Filed:
December 15, 1995
Date of Patent:
August 4, 1998
Assignee:
FMC Corporation
Inventors:
Daniel T. Hogan, Dale T. Bertrand, Marlene T. Tuazon, Domingo C. Tuason
Abstract: Dental products employing a ternary surfactant system of poloxamers, anionic polysaccharides, and nonionic cellulose ethers. This ternary surfactant system has greatly enhanced foaming power relative to poloxamers alone or to poloxamers plus anionic polysaccharides or to poloxamers plus nonionic cellulose ethers. The poloxamer-anionic polysaccharide-nonionic cellulose ether surfactant system has little or no taste, is nonirritating, and has excellent adhesion to tooth surfaces and oral mucosa. Inclusion of a mild abrasive plus one or more of xylitol, raw licorice, licorice extract, and glycyrrhizin and its derivatives enhances the clinical efficacy of the formulations by further reducing plaque buildup thus brightening teeth and reducing tooth decay and periodontal disease.The surfactant system can be used in a dentifrice paste or gel, powder, granules, disintegrable tablet, and a mouthwash, lozenge, and chewing gum.
Abstract: A purified and isolated cryIII-type gene was obtained from a novel B.t. strain. The gene has a nucleotide base sequence coding for the amino acid sequence illustrated in FIG. 1 . The 74.4 kDa protein produced by this gene is an irregularly shaped crystal that is toxic to coleopteran insects, including Colorado potato beetle and insects of the genus Diabrotica.
Type:
Grant
Filed:
September 24, 1992
Date of Patent:
January 17, 1995
Assignee:
Ecogen Inc.
Inventors:
William P. Donovan, Mark J. Rupar, Annette C. Slaney, Timothy B. Johnson
Abstract: A Bacillus thuringiensis strain isolate, designated EG5144, exhibits insecticidal activity against coleopteran insects, including Colorado potato beetle and insects of the genus Diabrotica. A novel toxin gene in B.t. strain EG5144 produces an irregularly shaped insecticidal crystal protein of approximately 70 kDa that is toxic to coleopteran insects. The cryIII-type gene (SEQ ID NO:1), designated as the cryIIIC(b) gene, has a nucleotide base sequence illustrated in FIG. 1.
Type:
Grant
Filed:
August 27, 1993
Date of Patent:
January 3, 1995
Assignee:
Ecogen, Inc.
Inventors:
William P. Donovan, Mark J. Rupar, Annette C. Slaney
Abstract: A Bacillus thuringiensis strain isolate, designated EG5092, exhibits insecticidal activity against lepidopteran insects. A purified and isolated novel cryET1 toxin gene product from B.t. strain EG5092 exhibits specific insecticidal activity against Plutella xylostella (Diamondback moth). The cryET1 gene (SEQ ID NO:1) has a nucleotide base sequence illustrated in FIG. 1 and produces a CryET1 gene product (SEQ ID NO:2) having a deduced amino acid sequence illustrated in FIG. 1.
Type:
Grant
Filed:
March 17, 1993
Date of Patent:
October 18, 1994
Assignee:
Ecogen Inc.
Inventors:
Michael A. von Tersch, Jose M. Gonzalez
Abstract: The present invention relates to a CryIIB protein which is insecticidal against lepidopteran insects, insecticidal compositions comprising the CryIIB protein and methods for use thereof.
Abstract: A Bacillus thuringiensis strain isolate, designated B.t. strain EG5847, exhibits insecticidal activity against lepidopteran insects. Two novel toxin genes from B.t. strain EG5847 designated cryET4 and cryET5 produce insecticidal proteins with activity against a broad spectrum of insects of the order Lepidoptera. The cryET4 gene has a nucleotide base sequence shown in FIG. 1 and listed in SEQ ID NO:1 and produces a CryET4 gene product having the deduced amino acid sequence shown in FIG. 1 and listed in SEQ ID NO:2. The cryET5 gene has a nucleotide base sequence shown in FIG. 2 and listed in SEQ ID NO:3 and produces a CryET5 gene product having the deduced amino acid sequence shown in FIG. 2 and listed in SEQ ID NO:4.
Type:
Grant
Filed:
July 29, 1993
Date of Patent:
June 21, 1994
Assignee:
Ecogen Inc.
Inventors:
William P. Donovan, Yuping Tan, Christine S. Jany, Jose M. Gonzalez, Jr.
Abstract: A Bacillus thuringiensis strain isolate, designated EG5144, exhibits insecticidal activity against coleopteran insects, including Colorado potato beetle and insects of the genus Diabrotica. A novel toxin gene in B.t. strain EG5144 produces an irregularly shaped insecticidal crystal protein of approximately 70 kDa that is toxic to coleopteran insects. The cryIII-type gene (SEQ ID NO:1), designated as the cryIIIC(b) gene, has a nucleotide base sequence illustrated in FIG. 1.
Type:
Grant
Filed:
March 15, 1993
Date of Patent:
November 23, 1993
Assignee:
Ecogen Inc.
Inventors:
Willam P. Donovan, Mark J. Rupar, Annette C. Slaney
Abstract: This invention relates to a crystalline protein toxin useful as a biological insecticide which is known as P-2 toxin, or P-2 delta-endotoxin and which is produced by Bacillus thuringiensis. More specifically, this invention relates to the cloning and expression in various microorganisms of the gene coding for the P-2 delta-endotoxin.
Abstract: A purified and isolated cryIII-type gene was obtained from a novel B.t. strain. The gene has a nucleotide base sequence coding for the amino acid sequence illustrated in FIG. 1. The 74.4 kDa protein produced by this gene is an irregularly shaped crystal that is toxic to coleopteran insects, including Colorado potato beetle and insects of the genus Diabrotica.
Type:
Grant
Filed:
March 20, 1990
Date of Patent:
February 16, 1993
Assignee:
Ecogen Inc.
Inventors:
William P. Donovan, Mark J. Rupar, Annette C. Slaney, Timothy B. Johnson
Abstract: Purified endotoxin protein is recovered from aqueous suspensions containing lysed cells and Bacillus thuringiensis crystalline endotoxin protein in a multistep process.The aqueous suspension, e.g., a concentrated fermentation culture, is first treated under strongly basic or acidic conditions to solubilize the crystal protein and the solution is then separated from residual solids. Endotoxin protein is precipitated from the separated aqueous solution, by adjusting its pH to the isoelectric point of the protein, and recovered by centrifugation or the like.
Abstract: The present invention provides novel strains of Bacillus thuringiensis containing genes that code for P1 endotoxin proteins. The invention also provides methods and compositions for controlling insects or protecting plants from insect attack with a novel strain of Bacillus thuringiensis.
Type:
Grant
Filed:
November 7, 1988
Date of Patent:
September 15, 1992
Assignee:
Ecogen Inc.
Inventors:
Ivan E. Gard, Jr., Jose M. Gonzalez, Jr., Dennis R. Ciarlante
Abstract: The present invention relates to novel Bacillus thuringiensis transconjugant strains having improved insecticidal activity. The novel strains are produced by a combination of plasmid curing and conjugation of active strains.
Type:
Grant
Filed:
April 25, 1988
Date of Patent:
January 14, 1992
Assignee:
Ecogen Inc.
Inventors:
Jose M. Gonzalez, Jr., Anthony Macaluso
Abstract: The present invention relates to a purified and isolated gene having a nucleotide sequence coding for the amino acid sequence for the CryIIB protein (the nucleotide coding sequence being illustrated in FIG. 6 extending from nucleotides 874 through 2775).
Abstract: The present invention relates to an in vitro method for measuring the toxicity of a delta-endotoxin of Bacillus thuringiensis by evaluating the ability of said endotoxin to form an ion channel in a phospholipid vesicle.
Abstract: Crystal solids made via the continuous crystallization of a crude, concentrated aqueous feed solution are recovered as a crystalline solid product that is relatively free of impurities present in the crystallizer liquor. A portion of the withdrawn crystallizer slurry is concentrated in a first hydroclone, diluted with crystallizer feed solution, concentrated in a second hydroclone, and centrifuged and dried to recover the crystalline solid product.
Type:
Grant
Filed:
July 27, 1984
Date of Patent:
November 1, 1988
Assignee:
Intermountain Research & Development Corporation
Abstract: Novel beta-1,3-glucan polysaccharide gels characterized by (a) coherent, uniform, non-particulate structure, and (b) substantially uniform pH throughout. The gels are prepared by dissolving a beta-1,3-glucan polysaccharide in an aqueous alkaline medium at a temperature of about 55.degree. C. or below and while maintaining the solution at a temperature of at least 50.degree. C., adjusting the pH to 10.5 or lower, followed by cooling below about 40.degree. C. or heating above 50.degree. C. The gels formed by cooling are reversible whereas the gels formed by heating are thermally irreversible. The gels are useful for supporting, separating, transforming or treating biological materials, as carriers for pharmaceuticals, as coatings for biological materials, in food products, and can be shaped to form disposable contact lenses.
Abstract: A particulate coprocessed microcrystalline cellulose and calcium carbonate composition having the respective components present in a weight ratio of from about 75:25 to 35:65. The composition is useful as a pharmaceutical excipient.The coprocessed composition is prepared by forming a well-dispersed aqueous slurry of microcrystalline cellulose and calcium carbonate and then drying the slurry, preferably by spray drying, to yield a particulate product.
Type:
Grant
Filed:
August 3, 1987
Date of Patent:
May 17, 1988
Assignee:
FMC Corporation
Inventors:
Dev K. Mehra, Kenneth P. West, J. Donald Wiggins
Abstract: A device for replicating moist bacterial or other cell colonies including a rigid layer, a resilient backing layer secured to one side of the rigid layer and a cell colony transfer surface made from an open-cell, flexible foam which includes a hydrophilic material therein and which surface is absorbent, porous, compliant and exhibits less resilience than said backing layer.
Abstract: A Well Indicating Device which is useful in laboratory procedures for identifying, in a predetermined but variable sequence, wells of a plurality fo independent but interrelated substance-receiving wells, such as of a microtiter tray, which are subject of manipulation.