Patents Represented by Attorney, Agent or Law Firm Clifford Chance
  • Use of procyanidins in the maintenance of vascular health and modulation of the inflammatory response
    Patent number: 6469053
    Abstract: Cocoa extracts which include procyanidin monomers and their oligomers are useful in the modulation of inflammatory pathways, in the maintenance of the vascular health of a mammal and as an antibacterial treatment. The liquid or dry cocoa extracts can be included in foods, food supplements and pharmaceuticals for the inhibition of COX activity, the inhibition of LOX activity, the enhancement of nitric oxide production, the modulation of eicosanoids and endothelin, and the modulation of platelet activity.
    Type: Grant
    Filed: February 18, 2000
    Date of Patent: October 22, 2002
    Assignee: Mars Incorporated
    Inventors: Leo J. Romanczyk, Jr., Harold H. Schmitz