Patents Represented by Attorney Colette C. Incyte Pharmaceuticals, Inc. Muenzen

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  • DNA hybridizing to a human cystatin-like protein (CSTIN)
    Patent number: 6110686
    Abstract: The present invention provides a human cystatin-like protein (CSTIN) and polynucleotides which identify and encode CSTIN. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding CSTIN and a method for producing CSTIN. The invention also provides for agonists, antibodies, or antagonists specifically binding CSTIN, and their use, in the prevention and treatment of diseases associated with expression of CSTIN. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding CSTIN for the treatment of diseases associated with the expression of CSTIN. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding CSTIN.
    Type: Grant
    Filed: May 19, 1999
    Date of Patent: August 29, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Surya K. Goli
  • Human phospholipase A2 protein
    Patent number: 6103469
    Abstract: The invention provides a human phospholipase A2 protein PHPLA2 and polynucleotides which identify and encode PHPLA2. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PHPLA2.
    Type: Grant
    Filed: November 7, 1997
    Date of Patent: August 15, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Phillip R. Hawkins, Olga Bandman, Karl J. Guegler, Purvi Shah, Neil C. Corley
  • Transducin beta-1 subunit
    Patent number: 6077688
    Abstract: The invention provides a human transducin beta-1 subunit (TBS) and polynucleotides which identify and encode TBS. The invention also provides expression vectors, host cells, agonists, antibodies, and antagonists. The invention also provides methods for treating or preventing diseases associated with expression of TBS.
    Type: Grant
    Filed: November 6, 1997
    Date of Patent: June 20, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Preeti Lal, Neil C. Corley, Purvi Shah
  • Human glutathione-S-transferase
    Patent number: 6071513
    Abstract: The invention provides a human glutathione-S-transferase (HGST) and polynucleotides which identify and encode HGST. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of HGST.
    Type: Grant
    Filed: January 8, 1999
    Date of Patent: June 6, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Henry Yue, Neil C. Corley, Purvi Shah
  • Calcium binding protein
    Patent number: 6071721
    Abstract: The invention provides a human calcium binding protein (hCBP) and polynucleotides which identify and encode hCBP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of hCBP.
    Type: Grant
    Filed: November 13, 1998
    Date of Patent: June 6, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Karl J. Guegler, Neil C. Corley, Gina A. Gorgone
  • Delayed rectifier potassium channel subunit
    Patent number: 6071720
    Abstract: The invention provides a human delayed rectifier potassium channel subunit (DRPCS) and polynucleotides which identify and encode DRPCS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of DRPCS.
    Type: Grant
    Filed: April 29, 1998
    Date of Patent: June 6, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Chandra Patterson, Neil C. Corley
  • G-protein coupled receptors associated with immune response
    Patent number: 6063596
    Abstract: The invention provides two human G-protein coupled receptors associated with immune response (GRIR) and polynucleotides which identify and encode GRIR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of GRIR.
    Type: Grant
    Filed: December 11, 1997
    Date of Patent: May 16, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Olga Bandman, Jennifer L. Hillman, Henry Yue
  • Human transferases
    Patent number: 6060250
    Abstract: The invention provides three human transferases (HUTRAN) and polynucleotides which identify and encode HUTRAN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HUTRAN.
    Type: Grant
    Filed: June 30, 1998
    Date of Patent: May 9, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Olga Bandman, Jennifer L. Hillman, Karl J. Guegler, Gina A. Gorgone, Neil C. Corley, Chandra Patterson
  • Human hyaluronidase
    Patent number: 6057110
    Abstract: The present invention provides a polynucleotide (hhp) which identifies and encodes a novel human hyaluronidase (HHP). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding HHP. The invention also provides for the use of substantially purified HHP and its agonists in the commercial production of recombinant proteins and in pharmaceutical compositions for the treatment of diseases associated with the expression of HHP. Additionally, the invention provides for the use of antisense molecules to hhp in pharmaceutical compositions for treatment of diseases associated with the expression of HHP. The invention also describes diagnostic assays which utilize diagnostic compositions comprising the polynucleotide, fragments or the complement thereof, which hybridize with the genomic sequence or the transcript of hhp. The present invention also relates to anti-HHP antibodies which specifically bind to HHP.
    Type: Grant
    Filed: December 17, 1998
    Date of Patent: May 2, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Janice Au-Young, Phillip R. Hawkins, Jennifer L. Hillman
  • Human vesicle binding protein
    Patent number: 6054290
    Abstract: The present invention provides a human vesicle binding protein (MVBP) and polynucleotides which identify and encode MVBP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing MVBP and for treating or preventing disorders associated with expression of MVBP.
    Type: Grant
    Filed: May 15, 1997
    Date of Patent: April 25, 2000
    Assignee: Incyte Pharamaceuticals, Inc.
    Inventors: Olga Bandman, Phillip R. Hawkins, Lynn E. Murry
  • Human retinoid binding protein
    Patent number: 6046027
    Abstract: The invention provides a human retinoid binding protein (RBPhu) and polynucleotides which identify and encode RBPhu. The invention also provides expression vectors, host cells, agonists, antibodies antagonists. The invention also provides methods for treating disorders associated with expression of RBPhu.
    Type: Grant
    Filed: July 22, 1997
    Date of Patent: April 4, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Karl J. Guegler, Purvi Shah
  • Cell surface glycoproteins
    Patent number: 6043056
    Abstract: The invention provides human cell surface glycoproteins (CSGP) and polynucleotides which identify and encode CSGP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CSGP.
    Type: Grant
    Filed: November 6, 1998
    Date of Patent: March 28, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Henry Yue, Neil C. Corley, Karl J. Guegler, Gina A. Gorgone, Mariah R. Baughn
  • Method for detecting HTRAN polynucleotides
    Patent number: 6037132
    Abstract: The present invention provides a human transcription factor (HTRAN) and polynucleotides which identify and encode HTRAN. The invention also provides expression vectors and host cells, agonists, antibodies, or antagonists. The invention provides methods for treating diseases associated with expression of HTRAN.
    Type: Grant
    Filed: June 16, 1999
    Date of Patent: March 14, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah
  • ATP synthase subunit homolog
    Patent number: 6036954
    Abstract: The invention provides a human ATP synthase subunit homolog (ASYNT) and polynucleotides which identify and encode ASYNT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of ASYNT.
    Type: Grant
    Filed: August 11, 1999
    Date of Patent: March 14, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn
  • Human microfibril-associated glycoprotein 4 splice variant
    Patent number: 6037163
    Abstract: The invention provides a human microfibril-associated glycoprotein 4 splice variant (MAG4V) and polynucleotides which identify and encode MAG4V. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of MAG4V.
    Type: Grant
    Filed: August 4, 1999
    Date of Patent: March 14, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Neil C. Corley, Purvi Shah
  • Human RNA binding proteins
    Patent number: 6020164
    Abstract: The invention provides human RNA binding proteins (RNABP) and polynucleotides which identify and encode RNABP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of RNABP.
    Type: Grant
    Filed: October 21, 1998
    Date of Patent: February 1, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Y. Tom Tang, Neil C. Corley, Karl J. Guegler, Dyung Aina M. Lu, Mariah R. Baughn
  • Cytikine signal regulators
    Patent number: 6020165
    Abstract: The invention provides human cytokine signal regulators (CKSR) and polynucleotides which identify and encode CKSR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CKSR.
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: February 1, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Henry Yue, Neil C. Corley, Karl J. Guegler, Mariah R. Baughn
  • Protein kinase homologs
    Patent number: 6013455
    Abstract: The invention provides human protein kinase homologs (PKH) and polynucleotides which identify and encode PKH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of PKH.
    Type: Grant
    Filed: October 15, 1998
    Date of Patent: January 11, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Y. Tom Yang, Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley, Gina A. Gorgone, Yalda Azimzai, Dyung Aina M. Lu
  • Kinesin-like motor protein
    Patent number: 6013454
    Abstract: The invention provides a human kinesin-like motor protein (KLIMP) and polynucleotides which identify and encode KLIMP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of KLIMP.
    Type: Grant
    Filed: September 28, 1998
    Date of Patent: January 11, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Y. Tom Tang, Neil C. Corley, Karl J. Guegler, Chandra Patterson
  • Human lysophosphatidic acid acyltransferase
    Patent number: 6001620
    Abstract: The invention provides a human lysophosphatidic acid acyltranferase (HLPAAT) and polynucleotides which identify and encode HLPAAT. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HLPAAT.
    Type: Grant
    Filed: March 1, 1999
    Date of Patent: December 14, 1999
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Henry Yue, Karl J. Guegler, Neil C. Corley