Abstract: A human monoclonal antibody, C5, specific for lipid A of the endotoxin core of Gram-negative bacteria and the hybridoma cell line which produces the antibody. The monoclonal antibody is produced by the fusion of lipid A sensitized lymphocytes and an appropriate fusion partner.
Type:
Grant
Filed:
August 25, 1993
Date of Patent:
June 20, 1995
Assignee:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Henry S. Kaplan, Abraham I. Braude, Nelson N. H. Teng