Patents Represented by Attorney Cooley Godward & Kronish LI

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  • Methods of quantifying methotrexate metabolites
    Patent number: 7563590
    Abstract: The present invention provides a method for efficiently converting methotrexate polyglutamates to methotrexate in a cellular extract by contacting the cellular extract with gamma glutamyl hydrolase under conditions suitable for efficient conversion of methotrexate polyglutamates to methotrexate.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: July 21, 2009
    Assignee: Cypress Bioscience Inc.
    Inventors: Thierry Dervieux, Russell B. Richerson