Abstract: A method for selecting base-curves for an ophthalmic lens according to given prescription data comprising the steps of: providing a base-curve series consisting of a plurality of base-curves; calculating a target lens according to the prescription data; calculating the base-curves calculated lenses according to the prescription data; selecting, for at least an optical parameter and/or a geometrical parameter, a threshold value for the difference between the base-curves calculated lenses values and the target lens value of said parameter(s); determining the list of the base-curves of the base-curve series where said difference for said parameter(s) is less or equal to the selected threshold value(s).

Abstract: Disclosed is a vibration damper comprising a cylinder in which a piston rod is guided in an axially movable manner. A first piston is mounted stationarily on the piston rod while a second piston that is equipped with at least one valve disk biased by a spring assembly is mounted on the piston rod so as to be axially movable counter to a force of at least one support spring. The spring assembly is provided with at least one spring plate on which the spring assembly rests. The second piston is retained by a fixing sleeve which supports the at least one spring plate. The structural unit encompassing the fixing sleeve and the at least one spring plate is fitted with an axially effective separating joint for a locking connection inside the structural unit. The entire structural unit can be axially displaced towards the at least one support spring.

Abstract: There is disclosed antibody molecules containing at least one CDR derived from a mouse monoclonal antibody having specificity for human TNF?. There is also disclosed a CDR grafted antibody wherein at least one of the CDRs is a hybrid CDR. Further disclosed are DNA sequences encoding the chains of the antibody molecules, vectors, transformed host cells and uses of the antibody molecules in the treatment of diseases mediated by TNF?.