Abstract: Method for making 6-substituted-1-hydroxy-2-pyridones, which may also be substituted in one or more of the 3-, 4-, and 5-positions, by reaction of the corresponding 2-pyrone with hydroxylamine or its salts in the presence of imidazole or a 2-aminopyridine which may be mono- or di-methyl substituted.
Abstract: A circuit for use with a control system in which interleaved pairs of records and parity characters following each interleaved pair of records are recorded on magnetic tape, with each of the interleaved pairs of records having at its ends a stop-command-forward character and a stop-command-reverse character, the circuit comprising gate means for passing read data from a magnetic tape reader to a utilization device, means for identifying the stop-command-reverse character and the stop-command-forward character, and a flip-flop for disabling the gate means in response to identification of one of the stop-command-characters at the end of a record and for enabling the gate means in response to identification of a different stop-command character at the beginning of a next record.
Abstract: Oxymethylene polymers are stabilized against the action of heat and oxygen by a stabilizer combination of an ester of a hydroxyl group containing araliphatic or aromatic carboxylic acid and an alkaline earth metal salt of an aliphatic, araliphatic or aromatic carboxylic acid. The efficiency of the stabilizer combination can be further improved by the addition of a costabilizer, especially a guanidine compound. The stabilized poly(oxymethylenes) are suitable for the manufacture of semifinished and finished articles.
Type:
Grant
Filed:
May 30, 1975
Date of Patent:
July 13, 1976
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Ernst Wolters, Heinz Schmidt, Karlheinz Burg, Gunter Sextro
Abstract: Pharmaceutical compositions acting on the metabolism which contain as active derivatives of the 4-hydroxy-3,5-di-akylphenyl-propionic acid corresponding to the formula I and II ##EQU1## wherein R.sub.1 and R.sub.2 which may be identical or different, each stands for an alkylradical having 1 to 8 carbon atoms,R.sub.3 stands for an alkylene radical having 2 to 12 carbon atoms,X stands for hydroxy, alkoxy having 1 to 18 carbon atoms, phenalkoxy having 1 to 4 alkyl carbon atoms, cycloalkoxy having 5 to 8 carbon atoms, --NR.sub.4 R.sub.5 in which R.sub.4 stands for an alkyl group having 1 to 18 carbon atoms, R.sub.5 stands for a hydrogen atom or R.sub.4 and R.sub.5 may form with the nitrogen atom a heterocyclic six-membered ring which may carry another hetero atom and n is an integer from 2 to 4 and process for preparing them.
Abstract: 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide or the nontoxic salts thereof is prepared by reacting 6-methyl-2,3-dihydro-1,3-oxazin-2,4-dione-3-sulfo-fluoride of the formula ##EQU1## with at least 1 mole water per mole of fluoride to obtain acetoacetamide-N-sulfo-fluoride with splitting off of CO.sub.2, treating the acetoacetamide-N-sulfofluoride with an aqueous and/or alcoholic base and isolating the oxathiazinone or the salts thereof.
Type:
Grant
Filed:
July 16, 1975
Date of Patent:
July 13, 1976
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Hartmut Pietsch, Karl Clauss, Erwin Schmidt, Harald Jensen
Abstract: The potassium salt practically free of fluoride of 6-methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide is prepared by cyclization of acetoacetamide-N-sulfofluoride with at least two moles potassium hydroxide, potassium methylate or a mixture of potassium hydroxide and potassium methylate per mole of sulfofluoride in methanol as solvent containing less than 50 % by weight of water at a temperature of from -20.degree. to +60.degree.C and separating the crystalline potassium salt of the oxathiazinone dioxide from the reaction solution. The compound obtained has a pure sweet taste.
Type:
Grant
Filed:
July 16, 1975
Date of Patent:
July 13, 1976
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Erwin Schmidt, Karl Clauss, Hartmut Pietsch, Harald Jensen
Abstract: New 1-hydroxy-2-pyridones of the general formula ##SPC1##In which R.sub.1 is alkyl of 1 to 17 carbon atoms, cycloalkyl of 5 to 8 carbon atoms, cyclohexylalkyl or phenalkyl both having 1 to 3 carbon atoms in the alkylene chain or .alpha.-furyl, all of which may be substituted by halogen, and R.sub.2 to R.sub.4 are hydrogen or lower alkyl, or two adjacent substituents together form a trimethylene or tetramethylene chain, and in which R.sub.1 to R.sub.4 together contain at least 2 carbon atoms, are prepared by contacting unsaturated .delta.-keto esters or mixtures thereof with hydroxylamine and subjecting the products to cyclization.
Abstract: Magnesidin, which comprises a mixture of the compounds of the general formula I ##SPC1##in which n is the integer 4 or 6, the magnesium-free form of Magnesidin, and the salts thereof with mono-or polyvalent cations, and a process for the preparation of Magnesidin which comprises cultivating pseudomonas magnesiorubra HPL No. Z-1190 (ATCC 21.856).
Type:
Grant
Filed:
August 15, 1974
Date of Patent:
July 6, 1976
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Julia Nazareth, Naren M. Gandhi, Pandurang V. Divekar, Noel J. DE Souza, Hans Kohl
Abstract: 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide and the nontoxic salts thereof are prepared by reacting acetoacetic acid with fluorosulfonyl isocyanate at a temperature of from -20.degree.C to +50.degree.C in the presence of from 0.5 to 2 moles, calculated on the FSI used, of an alkali methal fluoride or a tertiary amine of the formulaN(R.sub.1)(R.sub.2)(R.sub.3)in which R.sub.1, R.sub.2, R.sub.3 represent identical or different alkyl radicals having from 1 to 10 carbon atoms, two of the radicals R.sub.1 to R.sub.3 optionally form together an alkylene radical having from 4 to 5 carbon atoms which may contain N, O, or S as hetero atom, or one of the radicals R.sub.1 to R.sub.3 represents a phenyl radical, or of pyridine or quinoline, or of a mixture of the aforesaid compounds, and transforming the salt of acetoacetamide-N-sulfofluoride obtained into the oxathiazinone salt or the free oxathiazinone by a treatment with aqueous and/or alcoholic bases.
Type:
Grant
Filed:
July 16, 1975
Date of Patent:
July 6, 1976
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Karl Clauss, Erwin Schmidt, Hartmut Pietsch, Harald Jensen
Abstract: 6-Methyl-3,4-dihydro-1,2,3-oxathiazin-4-one-2,2-dioxide and the nontoxic salts thereof are prepared by reacting acetone and fluorosulfonyl isocyanate in a molar proportion of from 14:1 to 150:1 at a temperature of from 0.degree. to 60.degree.C, distilling off the excess acetone from the reaction mixture with acetoacetamide-N-sulfofluoride and bringing about cyclization by a treatment with bases at a pH of from 5 to 12. The oxathiazinone derivatives are used as sweeteners.
Type:
Grant
Filed:
July 16, 1975
Date of Patent:
July 6, 1976
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Karl Clauss, Hartmut Pietsch, Erwin Schmidt, Harald Jensen
Abstract: Tetanus antigen which contains a tetanus toxin inactivated with oxymethane sulfinate and a process for the manufacture of this tetanus antigen by the inactivation of a tetanus toxin which comprises treating the tetanus toxin with oxymethane sulfinate.
Abstract: Compositions comprising an effective amount of an active ingredient such as a medicinal agent, disinfectant, pesticide, insect repellant, or a cosmetic agent such as an antiperspirant, a bath oil, a fragrance, sunscreen, soap, hair dye, tanning agent, etc., in a carrier comprising a polymer comprising a monomer having hydrophilic functional groups such as hydroxyl, carboxyl, or amino groups and containing aluminum, zinc, or zirconium bound in complex form.
Abstract: The opening in a flexible container for wine and fruitjuice of a rubber-lined or coated synthetic fabric is closed by a gas- and liquidtight zipper. An easy and unproblematic cleaning of the container is possible due to the easy opening and closing of the zipper.
Type:
Grant
Filed:
September 10, 1974
Date of Patent:
June 29, 1976
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Theo Becker, Eduard Hilscher, Karl-Heinz Ott
Abstract: Process for the irregular dyeing of textile material, preferably in a continuous operation, by applying a mixture of dyestuffs and salts containing crystal water in powder form irregularly onto the material and melting the salt by means of a heat treatment, the bondage between the dyestuff and the material to be dyed being brought about by means of the liquid phase which forms thereby, and then finishing the dyeing in the usual manner according to known methods for the fixation of the dyestuffs used.
Type:
Grant
Filed:
August 22, 1974
Date of Patent:
June 29, 1976
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Walter Birke, Hans-Ulrich VON DER Eltz, Franz Schon
Abstract: Pellets which are manufactured from an elastic soft cellular plastics material having open pores of a volumetric weight of from 25 to 40 kg/m.sup.3 and having a number of 10 to 20/cm useful in a method for determining the vitality of tooth's pulpa.
Abstract: In a process for the preparation of tannable pelts from animal skins or hides wherein concurrent soaking, unhairing, opening up of the hide structure, and bating are effected in a single procedural step by treatment with enzymes in an aqueous bath containing enzymes, the improvement wherein the enzymatic treating bath is free of amines and comprises dissolved therein:A. an effective amount of at least one member selected from the group consisting of a fungus protease whose optimum efficacy towards casein is at a pH above 7.0, trypsin, papain, and a bacterial protease whose optimum efficacy is at a pH between 6 and 9;B. an effective amount of a bacterial protease having an optimum efficacy against hemoglobin at a pH above 9; andC. an effective amount of thioglycolic acid or a salt thereof.
Abstract: An automatic device for a rational management of animals, in particular of small animals, which essentially consists of a combination of an automatic feeder, a specially shaped watering valve and an automatic dung remover with the adequate cages.
Abstract: New valuable metal complex compounds, preferably copper, nickel, chromium or cobalt complex compounds, of monoazo dyestuffs which in the metal-free form and in form of the free acid correspond to the general formula (1) ##SPC1##In which one A stands for the group of the formula (2)HO -- R -- N = -- (2)wherein HO--R-- represents the radical of a coupling component of the series of the acetoacetic acid arylamide, barbituric acid, pyrazolone or of naphthalene, the hydroxyl group of which is in a vicinal position with regard to the azo group, and the other A stands for a hydroxyl group, X for a vinyl group or for a group having the formula --CH.sub.2 --CH.sub.
Type:
Grant
Filed:
October 26, 1973
Date of Patent:
June 29, 1976
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Fritz Meininger, Klaus Hunger, Hartmut Springer
Abstract: Triazino-benzimidazoles of the formula ##SPC1##In which R is a variety of substituents including alkyl, cycloalkyl, bi- and tricycloalkyl, phenyl and phenalkyl, are valuable fungicides.
Abstract: Diphenyl ethers of the formula ##SPC1##Wherein R.sub.1 represents hydrogen or halogen and R.sub.2 hydrogen or a monovalent cation, are intermediates for the manufacture of selective herbicides.