Patents Represented by Attorney, Agent or Law Firm Cynthia M. Soroos, Esq.
  • Tetracycline compounds for treatment of Cryptosporidium parvum related disorders
    Patent number: 6833365
    Abstract: Methods and compositions for treating Cryptosporidium parvum related disorders in a mammal are discussed. Several novel tetracycline compounds useful for treating Cryptosporidium parvum related disorders are also included.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: December 21, 2004
    Assignee: Trustees of Tufts College
    Inventors: Stuart B. Levy, Mark L. Nelson
  • 7-substituted tetracycline compounds
    Patent number: 6818635
    Abstract: The present invention pertains, at least in part, to novel 7-substituted tetracycline compounds. These tetracycline compounds can be used to treat numerous tetracycline compound-responsive states, such as bacterial infections and neoplasms, as well as other known applications for minocycline and tetracycline compounds in general, such as blocking tetracycline efflux and modulation of gene expression.
    Type: Grant
    Filed: June 29, 2001
    Date of Patent: November 16, 2004
    Assignees: Paratek Pharmaceuticals, Inc., Trustees of Tufts College
    Inventors: Mark L. Nelson, Roger Frechette, Peter Viski, Beena Bhatia, David Messersmith
  • 7-and 9-carbamate, urea, thiourea, thiocarbamate, and heteroaryl-amino substituted tetracycline compounds
    Patent number: 6818634
    Abstract: Substituted tetracycline compounds, methods of synthesis, and methods of use are discussed. Tetracyclines useful for treating tetracycline related disorders are also discussed. Intermediates useful for synthesizing other tetracycline compounds are also included.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: November 16, 2004
    Assignees: Paratek Pharmaceuticals, Inc., Trustees of Tufts College
    Inventors: Mark L. Nelson, Stuart B. Levy, Roger Frechette, Todd E. Bowser, Mohamed Y. Ismail
  • Methods and kits for the detection of arginine compounds
    Patent number: 6720188
    Abstract: Methods and kits for determine arginine compounds are discussed. The methods and kits of the invention can be used for the diagnosis of arginine compound associated disorders.
    Type: Grant
    Filed: July 5, 2001
    Date of Patent: April 13, 2004
    Assignees: FAL Diagnostics
    Inventors: Rima Kaddurah-Daouk, Thomas W. Bell, Alisher B. Khasanov
  • Use of creatine or creatine analogs for the treatment of diseases of the nervous system
    Patent number: 6706764
    Abstract: The present invention relates to the use of creatine compounds including creatine, creatine phosphate or analogs of creatine, such as cyclocreatine, for treating diseases of the nervous system. Creatine compounds can be used as therapeutically effective agents against a variety of diseases of the nervous system such as diabetic and toxic neuropathies, peripheral nervous system diseases, Alzheimer disease, Parkinson's disease, stroke, Huntington's disease, amyotropic lateral sclerosis, motor neuron disease, traumatic nerve injury, multiple sclerosis, dysmyelination and demyelination disorders, and mitochondrial diseases.
    Type: Grant
    Filed: May 7, 1997
    Date of Patent: March 16, 2004
    Assignees: Avicena Group, Inc., The General Hospital Corporation
    Inventors: Rima Kaddurah-Daouk, Ghaleb Daouk, M. Flint Beal