Abstract: Methanesulfonamides are structurally depicted by Formula I' ##STR1## or its pharmacologically acceptable salts where R.sub.3 is a C.sub.1-7 alkyl substituted with C.sub.3-7 cycloalkyl, or a C.sub.1-10 alkyl substituted with one to eight fluorine atoms, one to three hydroxy, one to three C.sub.1-5 acyloxy or one to three C.sub.1-4 alkoxy substituents. These compounds are useful as Class III antiarrhythmic agents and are stable against rapid metabolism. Methods for treating cardiac arrhythmias with the compounds of Formula I' as well as compositions thereof are also described.

Abstract: The present invention provides novel sulfonanilide and benzene-alkylaminium compounds which are the products of processes utilizing novel intermediates. Both the novel compounds and the novel intermediates are useful for the therapeutic or prophylactic treatment of arrhythmic activity.

Abstract: This invention encompasses novel analogs of Leukotriene B.sub.4 which are selected from a compound of formula I, B--C.apprxeq.C--CH.sub.2 C(M.sub.2)--C.apprxeq.C--Y--C(M.sub.1)--A, or formula II, B--C.apprxeq.C--CH.sub.2 C(M.sub.2)--C.apprxeq.C--P--R.sub.5 --A: wherein Y is: ##STR1## wherein P is: ##STR2## Patentable intermediates, process for making the novel analogs and intermediates and preparation of useful pharmacological agents comprising the analogs and intermediates are part of this invention.

Abstract: A process for preparing a porous random fiber polymeric composite sheet through the addition of a cellulose ether which is selectively soluble or insoluble to a random fiber composite slurry under conditions such that the cellulose ether is insoluble, forming the slurry into a sheet, fusing the organic polymer component of the sheet and heating the sheet to solubilize the cellulose ether whereby voids are formed in the sheet. Before the sheet is treated to remove the cellulose ether, it may be combined with other sheets and densified under heat and pressure. Before removing the cellulose ether, the densified sheet may be heated under reduced pressure to expand or loft the sheet in a direciton normal to the plane of the sheet. A random fiber polymeric composite sheet, a densified sheet and a lofted sheet, each comprising a binder, fusable organic polymer, reinforcing material and a cellulose ether are also provided. The same sheets after removal of the cellulose ether are further provided.

Abstract: A method for filtering liquid or gaseous materials where the filtration is conducted with a porous filter media prepared from an aqueous wet-laid, lofted fiber-reinforced composite sheet, the composite sheet comprising a heat fusible polymer, reinforcing fibers and a binder. The random fiber composite sheet can be selectively lofted or recompressed to form filter media having variable porosity. Also, a membrane support means prepared by applying or treating the fiber-reinforced composite sheet with a discriminating membrane layer.

Abstract: A method for accelerating the dehydration of aqueous dispersions and bonding the solids contained therein characterized by the addition of fly ash to the aqueous polymeric composition. The fly ash is added in an amount sufficient to significantly reduce the dehydration time of the composition and generally comprises at least a partial substitution of the mineral filler content of the aqueous polymeric dispersion.

Abstract: This invention is a novel high void volume fiber-reinforced resin composite having a continuous matrix of a thermoplastic resin and from about 10 to 50 percent by weight of randomly oriented short reinforcing fibers. A process for making such low density composites is also disclosed.

Abstract: Thermoplastic polymer blends containing normally incompatible polymers prepared by incorporating into one polymer repeating units containing pendant cyclic iminoether groups to form a first reactive polymer and another reactive polymer having coreactive groups to form a second reactive polymer which is capable of reacting with said first reactive polymer to form linkages between the polymers wherein said blend is characterized by said first or second reactive polymer being blended or extended with miscible polymer(s) to form a reactive blend thereof.

Abstract: Process for the polymerization of poly-2-alkyl-2-oxazoline characterized by employing ethylbenzene as the diluent. The ethylbenzene comprises from zero to about 40 percent by weight total polymer of the polymerization mixture. This process allows styrene polymerization equipment to be employed to polymerize poly-2-alkyl-2-oxazoline.

Abstract: A polymeric composition comprising a poly-2-oxazoline reacted by transamidation with a carboxylic acid, anhydride, salts of a carboxylic acid or combination thereof which can be blended with another polymeric composition to form a water wettable blend. In another aspect, the poly-2-oxazoline is crosslinked with a polybasic carboxylic acid by transamidation. The crosslinked polymeric composition is useful as an absorbent for polar materials.

Abstract: An improved aqueous slurry process for preparing reinforced polymeric composites in the absence of a flocculant comprising the steps of forming an alkaline aqueous slurry comprising a reinforcing material, a heat fusible organic polymer and a binder comprising a salt of an ethylene acrylic acid copolymer having an acrylic acid content from about 12 to about 30 percent by weight copolymer solids and adjusting the pH value of the slurry such that the binder is destabilized to coagulate the slurry. A product formed by the improved process is also provided.

Abstract: A process for modifying polymeric amine salts containing a halide ion by admixing with an epoxide to form a volatile halo-hydrin. By adjusting the amount of epoxide employed, the polymeric amine salt can be selectively modified by neutralization wherein partial or total conversion of the halide ion to a halo-hydrin is formed and by hydroxylation wherein the free amine sites formed from the conversion of the halide ion to a halo-hydrin are further reacted with excess epoxide to form a hydroxyl containing graft. The halo-hydrin is volatile and, therefore can be removed by distillation from the modified polymeric amine.

Abstract: A solid catalyst composition comprising a silica or silica-treated compound and a tin catalyst compound bonded to the surface of the silica compound which is not deactivated in the presence of silica or silica-treated compounds. A process for preparing the solid catalyst by contacting a silica compound containing reactive hydroxyl groups with a tin catalyst compound at a temperature range from about 130.degree. to 165.degree. C. under dynamic conditions whereby the tin catalyst compound bonds to the silica compound. Generally, after the reaction, at least a portion of the hydroxyl groups present on the silica compound are absent and, more preferably, substantially all the isolated hydroxyl groups are absent. A urethane composition containing the solid catalyst is also provided wherein the solid catalyst is not deactivated by the addition of silica or silica-treated compounds.