Abstract: Certain 3-(phenyl, chroman-2-yl, benzofuran-5-yl, or benzoxazol-5-yl)-2-(hydroxy or mercapto)propionic acid derivatives and analogs are useful as hypoglycemic and hypocholesterolemic agents.

Abstract: Optically active (C.sub.1 -C.sub.3) alkyl 2R-chroman-2-carboxylates are prepared by partial hydrolysis of the corresponding racemic ester using a microbial lipase as catalyst. Said 2R-chromancarboxylate is converted via novel 2R-(hydroxymethyl) chroman, 2R-(trifluoromethylsulfonyloxymethyl) chroman and 2R-benzylchroman intermediates into 2R-benzylchroman-6-carbaldehyde, a compound of known utility in the manufacture of certain hypoglycemic agents.

Abstract: This invention relates to certain polyamines found to be present in the venom of the Agelenopsis aperta spider. The polyamines of this invention and the salts thereof antagonize excitatory amino acid neurotransmitters, which neurotransmitters affect cells of various organisms, and are useful in antagonizing said neurotransmitters, per se, in the treatment of excitatory amino acid neurotransmitter mediated diseases and conditions and in the control of invertebrate pests. This invention also relates to compositions comprising said polyamines and salts thereof.

Abstract: A stepped frame having at least a pair of substantially planar surfaces oriented one lower than the other has a device for clamping a removable panel to the lower surface. One end of a rigid, unitary member attaches to the upper surface of the frame, while the other end extends over the panel, which in turn rests against the lower surface of the frame. A threaded aperture in the extending end, and a correspondingly threaded clamping screw cooperate to exert pressure on the panel when the screw is positively threaded through the aperture, thereby clamping the panel to the frame.