Abstract: The invention pertains to adjuvant and vaccine compositions of monophosphoryl lipid A, sugar and optionally an amine based surfactant, which when frozen and thawed or lyophilized and reconstituted reform a colloidal suspension having a light transmission of greater than or equal to 88% as measured spectrophotometrically.
Type:
Grant
Filed:
July 13, 1999
Date of Patent:
October 23, 2001
Assignee:
American Cyanamid Company
Inventors:
Vincent James LaPosta, John Hayward Eldridge