Abstract: Aspects of the invention include a sport accessory support stand. In some aspects, the sport accessory support stand is configured for retaining a sport accessory. In certain embodiments, the sport accessory support stand includes a base member and a support member wherein the support member is configured for being associated with the base member. In certain embodiments, the support member includes a plurality of post elements which extend away from the base member, wherein each of the post elements are positioned relative to one another so as to form a receptacle there between for receiving a portion of a sport accessory. In certain embodiments, the receptacle comprises a first width and a second width. For instance, in certain embodiments, the receptacle comprises a first width that is configured for receiving a portion of a bicycle, e.g., a front wheel portion, and the receptacle comprises a second width that is configured for receiving a portion of a scooter, e.g.

Abstract: Foldable or collapsible watercraft fins are described. Preferred examples of such fins are foldable surfboard, paddleboard, and kayak fins, one or more of which can be attached to a surfboard, paddleboard, or kayak.

Abstract: The present invention relates to the design, preparation and use of cascade regulatory circuits for amplification of gene expression. The genetic circuit is based on a plurality (e.g., two or more) of regulatory genes organized in a hierarchical order of expression in a genetic construct or constructs, which can be established in a cell, e.g., a gram-negative bacteria, by means of autoreplicative vectors or by chromosomal insertion. In one embodiment, the genetic construct(s) can be stabily maintained in the chromosome without selective pressure, and gene expression induced three orders of magnitude therefrom using economical biodegradable benzoate derivatives.

Abstract: A method is provided for introducing nucleic acid into a cell, by contacting the cell with a nucleic acid and applying a low electrical field impulse for a long pulse length. A method is provided for introducing a polypeptide into a cell, by contacting the cell with the polypeptide and applying a low electrical field impulse for a long pulse length.

Abstract: A method and apparatus for introducing a preselected molecule into a living cell by contacting the cell with the preselected molecule and applying a multiple series of electrical pulses to the cell. The method can be utilized ex vivo. The multiple electrical pulses generate rotating electric fields which introduce transient pores in the living cell without killing the cell. The rotating electric fields are provided in a flow through chamber apparatus having more than two electrodes. A three-step pulse process, e.g. collection, electroporation, electrophoresis, is used to introduce the preselected molecule into the cell. A mechanical means of repositioning cells between successive pulses is also provided. The apparatus can also provide a means to pulse cells at different temperatures and then after pulsing, let the cells recover for a specified residence time at another temperature.

Abstract: A method for delivery of an agent to a cell using electroporation is disclosed. The method includes positioning a first electrode and a second electrode such that an electrical signal passed between the first electrode and the second electrode passes through the cell. The method also includes passing an electrical signal between the first electrode and the second electrode, the electrical signal having a frequency greater than about 10 kHz. In one embodiment of the method, the electrical signal has a bipolar waveform. In another embodiment of the method, the electrodes are positioned at a treatment site, e.g., a tumor, for in vivo delivery of an agent.

Abstract: Various elements designed to protect an in-line skate frame from direct impact with damaging and/or abrasive surfaces are disclosed. Such protective elements mount to the skate frame and may be manufactured from various materials, including metals, plastics, composites, and ceramics. Also disclosed are methods of preventing direct impacts to or abrasions of a skate frame using the disclosed protective elements.

Abstract: Various means designed to protect an in-line skate frame from direct impact with damaging and/or abrasive surfaces are disclosed. Such protective means mount to the skate frame and may be manufactured from various materials, including metals, plastics, composites, and ceramics. Also disclosed are methods of preventing direct impacts to or abrasions of a skate frame using the disclosed protective means.

Abstract: The present invention relates to single and multiple layer collagen films that are useful for improved sustained release delivery of pharmaceuticals.

Abstract: Collagen-containing sponges comprising an absorbable gelatin sponge, collagen, and an active ingredient are disclosed as are methods of enhancing wound healing of external and internal wounds using such sponges.

Abstract: A class of subtilisin analogs suitable for admixture to cleaning compositions and having improved stability over naturally occurring Bacillus subtilisins are prepared by expressing a modified gene encoding the subtilisin analog in Bacillus subtilis.

Abstract: DNA molecules encoding a modified tryptophan synthase beta subunit are disclosed. When expressed in a recombinant host microorganism, these polypeptide analogs enable significant levels of intracellular indole production and accumulation. In the presence of an aromatic dioxygenase enzyme, the indole so produced can be converted to indoxyl, which upon exposure to air oxidizes to indigo.

Abstract: Erythropoietin (EPO) can be delivered systemically in therapeutically or prophylactically effective amounts by pulmonary administration using a variety of pulmonary delivery devices, including nebulizers, metered dose inhalers and powder inhalers. Aerosol administration of EPO in accordance with this invention results in significant elevation of red blood cell levels. EPO can be administered in this manner to medically treat or prevent anemia, as well as to treat or prevent other maladies related to erythropoiesis.

Abstract: A stable pharmaceutically acceptable formulation containing a pharmaceutically acceptable amount of a protein is disclosed. Also disclosed are associated means and methods for preparing such formulations.

Abstract: A method for reducing stored iron and serum iron in mammals is disclosed. In particular, a mammal having an iron overload disorder is administered a therapeutically effective amount of erythropoietin to increase red blood cell production and the mammal is subsequently phlebotomized to remove the excess red blood cells produced.

Abstract: The plant of the disclosure is a new and novel interspecific Guzmania plant, named `Puna Gold`, which is characterized as a perennial monocot of medium size which is vigorous; and, upright, spreading in habit. Flowering is conspicuously yellow and very long lasting with color retention of between about 3 to 6 months. Extension of inflorescence is about 43 to 48 cm. over a plant of about 72 to 82 cm in width. The plant produces between 36 to 40 leaves for optimum plant size and balance with inflorescence. Bracts and flower parts are brilliant and pale yellow, respectively, with flowers in tight groupings of 263 to 273 individual flowers.