Patents Represented by Attorney Daniel S. Kasten

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  • 3-(imidazolyl)-2-alkoxypropanoic acids
    Patent number: 6958402
    Abstract: Compounds according to formula (I) wherein n is 0-3, R1 is optionally substituted C1-6 alkyl, C2-6 alkenyl, or C2-6 alkynyl, Heterocycle, Aromatic heterocycle, Aryl or hydrogen and R2, R3, R4, R5, R6, R7, R8 and R9 are each independently selected from hydrogen and optionally substituted C1-6 alkyl, or R5 and R8 are an alkylene chain, are novel.
    Type: Grant
    Filed: March 29, 2004
    Date of Patent: October 25, 2005
    Assignee: Pfizer, Inc.
    Inventors: Charlotte Moira Norfor Allerton, David John Bull, Mark Edward Bunnage, Robert John Maguire, John Steele
  • Pharmaceuticals
    Patent number: 6949577
    Abstract: The present invention provides compounds of formula (I) as well as the use of such compounds in pharmaceutical compositions and methods of treatment. The compounds described herein represent a class of TAFIa inhibitors suitable for use in treating conditions such as thrombosis, atherosclerosis, adhesions, dermal scarring, cancer, fibrotic conditions, inflammatory diseases and those conditions which benefit from maintaining or enhancing bradykinin levels in the body.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: September 27, 2005
    Assignee: Pfizer, Inc.
    Inventors: Charlotte Moira Norfor Allerton, Julian Blagg, Mark Edward Bunnage, John Steele
  • 3-(imidazolyl)-2-aminopropanoic acids
    Patent number: 6919457
    Abstract: Compounds according to formula (I) wherein n is 1-4, R1 is optionally substituted C1-6 alkyl, C2-6 alkenyl, or C2-6 alkynyl, Heterocycle, Aromatic heterocycle, Aryl or hydrogen and R2, R3, R4, R5, R6, R7 and R8 are each independently selected from hydrogen and optionally substituted C1-6 alkyl are novel. They are useful in the treatment of thrombotic conditions and other pathologies associated with fibrin deposition.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: July 19, 2005
    Assignee: Pfizer, Inc.
    Inventors: Charlotte Moira Norfor Allerton, Mark Edward Bunnage, John Steele