Abstract: A clip for use in a cushion for a vehicle seat, wherein the cushion includes a cushioned pad and a trim cover , the cushioned pad having a recess portion and a wire embedded in the cushioned pad so as to be partially exposed to the recess portion from the cushioned pad, the trim cover having a portion, a longitudinal tensioning cord attached to the portion of the trim cover, a longitudinal bulged member provided along a longitudinal edge portion of the cord, and a laterally elongated through-hole formed in the cord.
Abstract: Methods and compositions relating to Alzheimer's disease are provided. Specifically, proteins that are differentially expressed in the Alzheimer's disease state relative to their expression in the normal state are provided. Proteins associated with Alzheimer's disease are identified and described. Methods of diagnosis of Alzheimer's disease using the differentially expressed proteins are also provided, as are methods for the identification and therapeutic use of compounds for the prevention and treatment of Alzheimer's disease.
Type:
Grant
Filed:
September 29, 2005
Date of Patent:
March 1, 2011
Inventors:
Jules Westbrook, Helen Byers, Malcolm Ward, Simon Lovestone, Abdul Hye, Stephen Lynham, Richard Joubert, Petra Prefot, Karsten Kuhn, Christian Baumann, Juergen Schaefer, Thorsten Prinz, Stefan Kienle
Abstract: Disclosed are devices for amplifying a preselected polynucleotide in a sample by conducting a polynucleotide amplification reaction. The devices are provided with a substrate microfabricated to include a polynucleotide amplification reaction, chamber, having at least one cross-sectional dimension of about 0.1 to 1000 ?m. The device also includes at least one port in fluid communication with the reaction chamber, for introducing a sample to the chamber, for venting the chamber when necessary, and, optionally, for removing products or waste material from the device. The reaction chamber may be provided with reagents required for amplification of a preselected polynucleotide. The device also may include means for thermally regulating the contents of the reaction chamber, to amplify a preselected polynucleotide. Preferably, the reaction chamber is fabricated with a high surface to volume ratio, to facilitate thermal regulation.
Type:
Grant
Filed:
August 11, 2003
Date of Patent:
February 22, 2011
Assignee:
Trustees of the University of Pennsylvania
Abstract: A catalyst, its method of preparation and its use for producing at least one of methacrolein and methacrylic acid, for example, by subjecting isobutane or isobutylene or a mixture thereof to a vapor phase catalytic oxidation in the presence of air or oxygen. In the case where isobutane alone is subjected to a vapor phase catalytic oxidation in the presence of air or oxygen, the product is at least one of isobutylene, methacrolein and methacrylic acid.
Abstract: An LED light may comprise a light emitting diode selectively energizable for producing light; an electronic circuit for selectively energizing the light emitting diode; and a heat sink of a thermally conductive material, wherein the light emitting diode is thermally bonded to the heat sink; and wherein the electronic circuit is attached to the heat sink. The light may have a pair of contact springs extending from the heat sink and the electronic circuit may include thermal conductivity enhancing features.
Abstract: Armor for a vehicle comprises a grid of bars, at least the majority of the bars being formed from carbon fiber. The carbon fiber bars may be pultruded and some of the bars may be metallic.
Type:
Grant
Filed:
September 4, 2007
Date of Patent:
February 8, 2011
Assignee:
NP Aerospace Limited
Inventors:
Roger Terence Arthur Medwell, Christopher Davies
Abstract: A method for suppressing narrowband interference in OFDM receivers is provided including the steps of acquiring a sample of received data, estimating parameters of each of a number of narrowband interferers from the acquired sample of data, forming an excision filter using the estimated parameters and inserting the excision filter into an OFDM receiver.
Abstract: A slide/flip-up type automobile-seat is disclosed. The seat is provided with lock-release restricting mechanisms provided at lower rail members of a slide rail mechanism for keeping slide lock levers in unlockable states with respect to the lower rail members during flipping-up movement of an entire seat or in a state where the entire seat has been flipped up, and for keeping striker locks in states of being unallowable to be unlocked when the lock levers are in states of incompletely locked with respect to the lower rail members. Each of the lock-release mechanisms includes a restricting arm which includes an arm body, a rising-up piece rising up from one end portion of the arm body and having a height reaching a position under a rear end portion of corresponding one of the lock levers, and a retaining piece which is provided at a side edge of the arm body and to which a corresponding one of extension rods extending from the striker locks is connected.
Abstract: A trampoline comprising a flexible mat (3) and a plurality of springs (4) holding the mat in tension within a peripheral frame (1) of the trampoline which surrounds the mat has an enclosure system surrounding the mat. The enclosure has a lower peripheral part coupled to the mat and a plurality of resiliently flexible upright enclosure members (5) to support the barrier above the mat. The enclosure support members are free to resiliently deform away from the mat when impacted by a user against the barrier. They are also connected together at the upper ends of the enclosure support members away from their natural rest state and towards the center of the mat. When impacted by a user against the barrier on the side of the enclosure causing the barrier to resiliently deform away from the mat, the enclosure support members are resiliently deformed towards the center of the mat.
Abstract: A microchip device is disclosed that combines a signal attenuator and a frequency filter. An embodiment of the device includes an input contact, an output contact, and a ground contact formed on the surface of a substrate. Resistive elements formed on the substrate interconnect the contacts. At least the input contact includes a gap pattern formed therein that is dimensioned and arranged such that the input contact provides a reactive impedance characteristic. The combination of the resistance of the resistive elements and the reactive impedance characteristic of the input contact are selected to provide attenuation and frequency filtering of a high frequency signal input to the microchip device. A method of manufacturing the filter-attenuator microchip device is also described.
Abstract: The present invention relates to high-throughput cell-based assays for real-time monitoring of multi-resistant drug protein activity. The present invention is an improvement over existing assays in that in addition to a fluorescent drug efflux probe as an indicator of MDR protein activity, the instant assays provide an o-tolidine-based dye for quenching extracellular fluorescence of the probe.
Type:
Grant
Filed:
February 23, 2007
Date of Patent:
November 23, 2010
Assignee:
Board of Regents of the University of Nebraska
Inventors:
Donald W. Miller, Corbin J. Bachmeier, Richard B. Lomneth
Abstract: A water based drilling fluid contains as additive one or more alkyl ethoxylates having the formula RO(CH2CH2O)nH; wherein: R is a C16-22alkyl group (preferably R is aliphatic and more preferably R is linear), and n is an integer in the range 2-30. The fluid further contains one or more viscosifying agents, and is substantially clay-free.
Abstract: A height adjusting device for an automobile seat is disclosed. The height adjusting device includes a sector gear (13) arranged between a side frame section (1) of a seat cushion frame of the seat and a linkage arm (2) and supported to a fixing pin (2a) of the linkage arm (2), a plating pin (16) for interconnecting the linkage arm (2) and a linkage rod (4), the planting pin (16) being provided at the sector gear (13), and a spiral spring (14) stretched between the fixing pin (2a) projected from the linkage arm (2) and the planting pin (16) with an innermost end portion (14a) thereof being retained around an end of the fixing pin (2a), and with an outermost end portion (14b) thereof being retained around an end of the planting pin (16).
Abstract: An isolated nucleic acid molecule encoding a human DNA repair enzyme, MED1, is disclosed. Like other mismatch repair genes which are mutated in certain cancers, MED1, encoding nucleic acids, proteins and antibodies thereto may be used to advantage in genetic or cancer screening assays. MED1, which recognizes and cleaves DNA, may also be used for the diagnostic detection of mutations and genetic variants.
Abstract: There is disclosed a vehicle seat provided with a system for facilitating relieving of fatigue of an occupant on the vehicle seat, the vehicle seat including a seat back, the system comprising an occupant's body-motion promoting means 6 provided in an interior of the seat back 1 for repeatedly locally pressing the occupant on the vehicle seat, to thereby promote blood circulation of the occupant, a lateral acceleration sensor 8 provided in the interior of the seat back 1 for detecting accelerations that are applied in right and left lateral directions relative to a vehicle, and an acceleration-distinction control circuit provided in the interior of the seat back 1 for causing the body-motion promoting means 6 to be maintained in a drivable state according when an acceleration detected by the lateral acceleration sensor 8 is in a predetermined value range, for causing drive of the body-motion promoting means to be once stopped when the lateral acceleration becomes an excessive value exceeding an upper limit of
Abstract: Disclosed are compositions and methods for enhancing the yield of coagulated milk products including cheese and other fermented milk products. Admixture of structurally expanded celluloses into milk allows substantial incorporation of additional whey solids and fluids into the caseinate matrix. The resulting interactive particle network comprising the cellulosic microfibril substructure and caseinate curd is readily manipulated by standard methods employed in the dairy industry to produce a variety of natural and processed dairy products with increased yield.
Abstract: A storm panel is provided for shielding a structure. The storm panel includes at least one corrugation, and comprises a first wall and a second wall disposed in spaced-apart relation. An angled wall is disposed between and connected to the first wall and the second wall to support the second wall away from the first wall. At least one ridge is disposed proximate the point of connection between the second wall and the angled wall, and may have a shape configured to strengthen the panel proximate the point of connection between the second wall and the angled wall. In addition, a storm panel assembly is provided comprising at least one storm panel and a mounting extrusion for attachment to the storm panel to provide support for the storm panel on a mounting surface, such as the side of a building.
Type:
Grant
Filed:
August 24, 2007
Date of Patent:
August 17, 2010
Inventors:
Shawn Milliken, Les Milliken, Kim Smiley
Abstract: Disclosed are devices for detecting the presence of a preselected analyte in a fluid sample. The devices comprise a substrate microfabricated to define a sample inlet port, and a mesoscale flow system that includes a sample flow channel extending from the inlet port. The mesoscale flow system further includes an analyte detection region in fluid communication with the flow channel comprised of a binding moiety for specifically binding the analyte. The detection region is constructed with a mesoscale dimension sufficiently small to enhance binding of the binding moiety and the analyte. The binding moiety may be immobilized in the detection region. The mesoscale detection systems of the invention may be used in a wide range of applications, including the detection of cells or macromolecules, or for monitoring reactions or cell culture growth.
Type:
Grant
Filed:
April 4, 2007
Date of Patent:
August 10, 2010
Assignee:
Trustees of the University of Pennsylvania
Inventors:
Peter Wilding, Larry J. Kricka, Jay N. Zemel