Abstract: A polynucleotide encoding a secreted form of wild type Renilla luciferase. Also provided is a polynucleotide encoding a secreted modified form of wild type Renilla luciferase. Additionally, the polypeptides encoded by the polynucleotides of the present invention and uses of the polynucleotides and polypeptides of the present invention in biological assays. Also, a stable mammalian packaging cell line which produces retroviruses carrying a polynucleotide encoding a secreted Renilla luciferase.

Abstract: A method for selectively detecting the presence of C. parvum organisms in a sample. A method for selectively detecting the presence of C. parvum organisms and for detecting the presence of G. lamblia organisms, simultaneously, in a sample. A method for selectively detecting viable C. parvum organisms in a sample potentially containing viable C. parvum organisms. A method for selectively detecting viable C. parvum organisms and for detecting viable G. lamblia organisms, simultaneously. A method for selectively detecting infectious C. parvum organisms in a sample, and in another embodiment, additionally comprising detecting viable G. lamblia organisms in the sample, simultaneously. Kit for use in performing these methods.

Abstract: A method for the disposal of biosolids, such as municipal sewage waste, comprising injecting the biosolids into a subsurface injection formation. The method can include recovering methane generated from the degradation of the biosolids.

Abstract: A method of decreasing the signs or symptomatology in a patient with a neurologic condition or disease, or in a patient due to effects of exposure to an exogenous substance, such as a pharmaceutical agent, comprising selecting a patient having at least one sign or symptom selected from the group consisting of akinesia, bradykinesia, dyskinesias, gait disturbances, posture disturbances, rigid limbs, speech impairments and tremor and administering to the patient one or more than one effective doses of a phosphodiesterase inhibitor.

Abstract: A method of determining the presence and identity of a variation in a nucleotide sequence between a first polynucleotide and a second polynucleotide comprising, first, providing a sample of the first polynucleotide and selecting a region of the first polynucleotide potentially containing the variation. Then, the selected region is subjected to a template producing amplification reaction to produce a plurality of double stranded polynucleotide templates which include the selected region. Next, a family of labeled, linear polynucleotide fragments is produced from both strands of the template simultaneously by a fragment producing reaction using a set of primers. Then, the location and identity of at least some of the bases in the selected region of the first polynucleotide is determined using the labels present in the fragments.

Abstract: An isolated polynucleotide encoding motoneuronotrophic factor F6.

Abstract: A method for altering iris pigmentation in a human, thereby altering perceived iris color of a first iris from a first iris color to a second iris color. The method comprises preselecting one or more than one laser capable of generating one or more than one laser beam which will selectively remove iris pigment of a first preselected pigment color from the first iris, and applying the one or more than one laser beam to the first iris of a first iris color to remove iris pigment of the first preselected pigment color.

Abstract: A method for the disposal of biosolids, such as municipal sewage waste, comprising injecting the biosolids into a subsurface injection formation. The method can include recovering methane generated from the degradation of the biosolids.

Abstract: A vertebral traction device for applying traction to the cervical vertebral column. A method for applying traction to the cervical vertebral column.

Abstract: A non-virulent, recA defective mutant of Porphyromonas gingivalis. The Porphyromonas gingivalis strain which is deposited at ATCC under accession number 202109. Also a method of decreasing the growth rate or reproduction rate of Porphyromonas gingivalis in a mammal comprising the step of administering to the mammal at least one dose of Porphyromonas gingivalis according to the present invention. Further, a method of preventing or treating a Porphyromonas gingivalis infection such as periodontitis in a mammal comprising the step of administering to the mammal at least one dose of Porphyromonas gingivalis according to the present invention. Also, a pharmaceutical composition comprising a non-virulent, recA defective mutant of Porphyromonas gingivalis.

Abstract: A calcium-based ophthalmic composition for treating dry eye including a hydrophobic carrier, such as petrolatum, and a calcium salt. Also a method for treating dry eye comprising the step of administering the composition according to the present invention.

Abstract: A polynucleotide encoding a secreted form of wild type Renilla luciferase. Also provided is a polynucleotide encoding a secreted modified form of wild type Renilla luciferase. Additionally, the polypeptides encoded by the polynucleotides of the present invention and uses of the polynucleotides and polypeptides of the present invention in biological assays. Also, a stable mammalian packaging cell line which produces retroviruses carrying a polynucleotide encoding a secreted Renilla luciferase.

Abstract: A method of preparing a beta titanium-composite laminate comprising providing a first layer of beta titanium alloy having a yield strength to modulus of elasticity ratio and adhering a first layer of composite having a strength to modulus of elasticity ratio to the layer of beta titanium alloy, thereby forming a beta titanium-composite laminate, where the yield strength to modulus of elasticity ratio of the first layer of beta titanium alloy matches the strength to modulus of elasticity ratio of the first layer of composite such that the first layer of beta titanium alloy will reach its stress limit and the first layer of composite will reach its stress limits at about the same total strain.

Abstract: A vertebral traction device for applying traction to the lower vertebral column. A method for applying traction to the lower vertebral column.

Abstract: A method for detecting an analyte in a sample uses both the specificity of an enzymatic reaction and the separation power of capillary electrophoresis.

Abstract: A system and method for detection of electrical bioimpedance signals in a human or animal body segment. The system comprises a constant current generator for generating a periodic high frequency current output across a body segment in response to a periodic control input signal, a controller for generating a periodic control output signal to control operation of the current generator and an electrical bioimpedance detector for detecting a voltage generated across the body segment by the flow of current in the segment. The electrical bioimpedance detector generates an output signal indicative of bioimpedance in the body segment. The periodic generation of a current across a body segment alleviates the potentially detrimental effects of a continuous current on body segment tissue and reduces interference with the function of certain pacemakers.

Abstract: A system and method for detection of electrical bioimpedance signals in a human or animal body segment. The system comprises a constant current generator for generating a periodic high frequency current output across a body segment in response to a periodic control input signal, a controller for generating a periodic control output signal to control operation of the current generator and an electrical bioimpedance detector for detecting a voltage generated across the body segment by the flow of current in the segment. The electrical bioimpedance detector generates an output signal indicative of bioimpedance in the body segment. The periodic generation of a current across a body segment alleviates the potentially detrimental effects of a continuous current on body segment tissue and reduces interference with the function of certain pacemakers.

Abstract: A new distinct variety of strawberry plant that produces equivalent yields of equally high quality fruit in both fumigated and non-fumigated conditions, is resistant to many common foliar and soil borne diseases and pests and has unusually excellent fruit flavor and aroma.

Abstract: A new and distinct variety of strawberry plant named ‘Cal Giant 3’ that produces equivalent yields of equally high quality fruit in both fumigated and non-fumigated conditions, is resistant to many common foliar and soil borne diseases and pests, and has unusually execellent fruit flavor and aroma. Further, ‘Cal Giant 3’ has the potential to out-produce all currently grown varieties during the first half of the season, and to equal or exceed total season production of all currently grown varieties.

Abstract: A new and distinct variety of strawberry plant named ‘Cal Giant 4’ that produces equivalent yields of exceptionally high quality fruit in both fumigated and non-fumigated conditions, is tolerant of many common root, foliar, and fruit diseases and pests, produces exceptionally well-pollinated fruit in inclement conditions, maintains exceptional size and shape throughout the harvest season, and has exceptional flavor.