Patents Represented by Attorney David A. Sheldon & Mak Farah
  • Patent number: 6164288
    Abstract: A tobacco smoke filter containing a porous substrate having dry water and microcapsules dispersed therein. The microcapsules contain at least one compound selected from the group consisting of chlorophyllin, methylcellulose, sodium pyroglutamate and a vegetable oil. The tobacco smoke filter can also contain one or more substances such as a porphyrin, and sodium pyroglutamate.
    Type: Grant
    Filed: September 17, 1999
    Date of Patent: December 26, 2000
    Assignee: Craig Lesser
    Inventors: Craig Lesser, Reid W. Von Borstel
  • Patent number: 6156028
    Abstract: A laser insole having one or many vertical cavity surface emitting lasers embedded therein may be worn by a patient and applied to an area of the foot. The device supplies the patient with a preprogrammed laser therapy regimen. A physician programs the device and inserts the device in a patient's shoe. The device is small enough to allow the patient's normal activities. The laser therapy regimen promotes healing of a wound on the foot. Alternatively, the device may adapted as a flexible device applied to the skin, or implanted into the body, or provided in a catheter that is inserted into a body region.
    Type: Grant
    Filed: February 18, 1998
    Date of Patent: December 5, 2000
    Inventor: Marvin A. Prescott
  • Patent number: 6150136
    Abstract: A protein consisting essentially of purified oligodendrocyte-specific protein or purified biologically active variants thereof, or a combination of purified oligodendrocyte-specific protein and biologically active variants thereof. A purified and isolated peptide having the sequence Ala-Lys-Tyr-Arg-Arg-Ala-Gln-Leu-Ala-Gly, residues 115-124 of SEQ ID NO:2.
    Type: Grant
    Filed: May 22, 1998
    Date of Patent: November 21, 2000
    Assignees: The Regents of the University of California, Research Genetics, Inc.
    Inventors: Jeff M. Bronstein, Robert S. Seitz, Roger L. Lallone
  • Patent number: 6147052
    Abstract: A method of differentiating erythrocyte progenitor cells comprising administering to the erythrocyte progenitor cells an effective amount of an Erythroid Differentiation and Denucleation Factor (EDDF), such that the erythrocyte progenitor cells differentiate.
    Type: Grant
    Filed: August 29, 1997
    Date of Patent: November 14, 2000
    Assignee: KM Biotech, Inc.
    Inventor: Raymond Ming Wah Chau
  • Patent number: 6147191
    Abstract: A protein consisting essentially of purified oligodendrocyte-specific protein or purified biologically active variants thereof, or a combination of purified oligodendrocyte-specific protein and biologically active variants thereof. A purified and isolated peptide having the sequence Ala-Lys-Tyr-Arg-Arg-Ala-Gln-Leu-Ala-Gly, residues 115-124 of SEQ ID NO:2. A device for identifying an epitope region of a peptide, protein, or protein homologue of interest comprising a polypropylene membrane having a plurality of sequentially oriented peptide spots, each spot containing a peptide having an amino acid sequence where the amino acid sequences of the peptides on the peptide spots sequentially progress through the amino acid sequence of the peptide, protein, or protein homologue of interest. A method of diagnosing multiple sclerosis and a method of treating multiple sclerosis.
    Type: Grant
    Filed: May 26, 1998
    Date of Patent: November 14, 2000
    Assignee: The Regents of the University of California
    Inventors: Robert S. Seitz, Roger L. Lallone, Jeff M. Bronstein
  • Patent number: 6110740
    Abstract: A polynucleotide encoding a human vault-associated vRNA or its complementary strand. A purified and isolated polynucleotide molecule consisting essentially of a human vault RNA, or its complementary strands, or a combination of a nucleotide sequence consisting essentially of a human vault RNA and its complementary strands. A method of diagnosing a patient with a multidrug-resistant cancer. A method of treating a patient with multidrug-resistant cancer. A composition for treating multidrug-resistant cancer comprising a polynucleotide which hybridizes with a human vault-associated vRNA. A method of screening for compositions for treating a patient with multidrug-resistant cancer.
    Type: Grant
    Filed: March 26, 1999
    Date of Patent: August 29, 2000
    Assignee: Regents of the University of California
    Inventors: Leonard H. Rome, Valerie A. Kickhoefer
  • Patent number: 6050433
    Abstract: A container closure includes an access, which can receive a drinking straw, which is able to be folded down into a groove by the pivotal movement of member, which closes off the drinking straw by engaging it across an upstanding flange or projection.
    Type: Grant
    Filed: August 29, 1997
    Date of Patent: April 18, 2000
    Assignee: The Hanger Company Limited
    Inventors: Allin Nicholas Russell, James Richard Manley
  • Patent number: 5975086
    Abstract: A tobacco smoke filter consisting essentially of a porous substrate having dry water and microcapsules dispersed therein. The microcapsules comprise at least one substance selected from the group consisting of chlorophyllin, methylcellulose, sodium pyroglutamate and a vegetable oil.
    Type: Grant
    Filed: January 26, 1998
    Date of Patent: November 2, 1999
    Assignee: Craig Lesser
    Inventors: Craig Lesser, Reid W. Von Borstel
  • Patent number: 5860428
    Abstract: A cigarette filter comprises a humectant, preferably sodium pyroglutamate, and optionally a surfactant. The humectant absorbs moisture from the tobacco smoke for wet-filtration of the tobacco smoke.
    Type: Grant
    Filed: October 13, 1995
    Date of Patent: January 19, 1999
    Assignee: Craig Lesser
    Inventors: Craig Lesser, Reid W Von Borstel
  • Patent number: 5839447
    Abstract: A tobacco smoke filter with a porous substrate having a humectant, such as sodium pyroglutamate, dispersed therein to absorb moisture from the tobacco smoke thereby wet-filtering the tobacco smoke. Also, a tobacco smoke filter with a porous substrate having microcapsules dispersed therein. The microcapsules have a humectant such as sodium pyroglutamate. The microcapsules further preferably have one or more of methylcellulose, chlorophyllin and at least one vegetable oil.
    Type: Grant
    Filed: October 31, 1996
    Date of Patent: November 24, 1998
    Inventors: Craig Lesser, Reid W. Von Borstel
  • Patent number: 5830450
    Abstract: A composition for diagnosing or treating abnormalities in the endogenous leptin pathway in a subject mammal consisting essentially of apolipoprotein J bound to leptin or comprising a purified form of apolipoprotein J bound to leptin. A method for diagnosing abnormalities in the endogenous leptin pathway in a subject mammal. A method for treating abnormalities in the endogenous leptin pathway in a subject mammal. A method for determining the presence or amount of leptin that is associated with apolipoprotein J in a test sample. A kit for performing the method for determining the presence or amount of leptin that is associated with apolipoprotein J in a test sample.
    Type: Grant
    Filed: June 19, 1996
    Date of Patent: November 3, 1998
    Inventor: Roger L. Lallone
  • Patent number: 5830508
    Abstract: A calcium-based ophthalmic composition for treating dry eye is disclosed. The composition includes a hydrophobic carrier such as petrolatum and a calcium salt. The composition can further include a polyol such as glycerol, and an agent such as anhydrous lanolin, to enhance the interface between the carrier, and the calcium salt and polyol. Also disclosed is a method for treating dry eye comprising the step of administering the composition according to the present invention by placing the composition on the lateral portion of the lower eyelid margin. This method allows the composition to gradually disperse onto the cornea and conjunctiva.
    Type: Grant
    Filed: January 21, 1997
    Date of Patent: November 3, 1998
    Assignee: Deo Corporation
    Inventor: Donald L. MacKeen
  • Patent number: 5816676
    Abstract: A work glove and illuminator assembly is provided. An illuminator is securely mounted on the glove and oriented to project a light beam distally of the glove toward the work surface when the glove is in use. The illuminator may have a self-contained light source, or utilize fiber optic-transmitted light from a light source remote from the glove. The assembly may comprise a laser generator or may utilize a fiber optic-transmitted laser light from a laser generator remote from the glove. The assembly may further comprise a video camera operably attached to a video receiver, a video monitor and/or a video recorder. In one embodiment of the invention, the illuminator is disposed within the interior of the glove and projects a beam of light through a glove tip which is translucent or transparent. The assembly is particularly suitable for use by health care professionals when examining or operating upon an anatomical part of a patient.
    Type: Grant
    Filed: February 22, 1996
    Date of Patent: October 6, 1998
    Inventors: Howard P. Koenen Myers, Raymond W. Trow
  • Patent number: 5779658
    Abstract: A protective garment for the hip, including the hip joint, that comprises a pair of loose fitting or form-fitting shorts having an upper right lateral section, a lower right lateral section, an upper left lateral section, a lower left lateral section and a lower back section. The garment fruther comprises protective padding in combination with one or more of these section. The padding in combination with the upper right lateral section is separated from the padding in combination with the lower right lateral section by a first gap, and the padding in combination with the upper left lateral section is separated from the padding in combination with the lower left lateral section by a second gap. The first and second gaps comprise substantially unpadded flexible material thereby allowing substantially unhindered flexion and abduction of the hip joint. The padding can be compartmentalized or noncompartmentalized and can be in a variety of configurations.
    Type: Grant
    Filed: May 13, 1997
    Date of Patent: July 14, 1998
    Inventor: Ricardo E. Saca
  • Patent number: 5776097
    Abstract: A device and method for the therapeutic management of intracranial vascular aneurysms are provided involving the use of intravascular balloon catheters that can directly image the aneurysm and that can occlude the entire lumen of the aneurysm sac using liquid sealing agents. The intracranial catheters, according to the present invention, have various configurations designed to treat aneurysms regardless of the aneurysm's neck size and at different locations within the intracranial vascular system.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: July 7, 1998
    Assignee: University of California at Los Angeles
    Inventor: Tarik F. Massoud
  • Patent number: 5770368
    Abstract: The subject invention provides processes and kits for detecting encysted forms of protozoa, particularly Cryptosporidium and Giardia, that are viable and infectious. To determine viability, cysts or oocysts are heated to a temperature that induces transcription of heat shock protein (HSP) genes. Alternatively, to determine infectivity the encysted forms are inoculated onto susceptible cell cultures. The viability or infectivity of the encysted forms can be determined by synthesizing a cDNA from an induced HSP RNA template using a primer that is specific for particular genus or species of protozoa, followed by enzymatic amplification of the cDNA. Alternatively, infectivity can be determined by amplifying HSP DNA from infected cells using a primer pair that is specific for a particular genus or species of protozoa. Amplified HSP DNA can be detected using probes that are specific for a protozoan species of interest, such as the human pathogens C. parvum and G. lamblia.
    Type: Grant
    Filed: May 9, 1996
    Date of Patent: June 23, 1998
    Assignee: Metropolitan Water District of Southern California
    Inventors: Ricardo De Leon, Paul A. Rochelle
  • Patent number: 5756300
    Abstract: A protein consisting essentially of purified oligodendrocyte-specific protein or purified biologically active variants thereof, or a combination of purified oligodendrocyte-specific protein and biologically active variants thereof. A purified and isolated peptide having the sequence Ala-Lys-Tyr-Arg-Arg-Ala-Gln-Leu-Ala-Gly residues 115-124 of SEQ ID NO:2. A device for identifying an epitope region of a peptide, protein, or protein homologue of interest comprising a polypropylene membrane having a plurality of sequentially oriented peptide spots, each spot containing a peptide having an amino acid sequence where the amino acid sequences of the peptides on the peptide spots sequentially progress through the amino acid sequence of the peptide, protein, or protein homologue of interest. A method of diagnosing multiple sclerosis and a method of treating multiple sclerosis.
    Type: Grant
    Filed: November 14, 1995
    Date of Patent: May 26, 1998
    Assignees: Research Genetics, Inc., University of California at Los Angeles
    Inventors: Robert S. Seitz, Roger L. Lallone, Jeff M. Bronstein
  • Patent number: 5746231
    Abstract: A tobacco smoke filter comprising a porous substrate having a humectant, such as sodium pyroglutamate, dispersed therein to absorb moisture from the tobacco smoke thereby wet-filtering the tobacco smoke. The tobacco smoke filter can also comprise a porous substrate having microcapsules dispersed therein. The microcapsules can comprise a humectant such as sodium pyroglutamate. The microcapsules further preferably comprise one or more of methylcellulose, chlorophyllin and at least one vegetable oil. The tobacco smoke filter can also comprise a porous substrate having dry water and a porphyrin dispersed therein. The tobacco smoke filter can also comprise a porous substrate having a copper-containing porphyrin dispersed therein.
    Type: Grant
    Filed: May 15, 1996
    Date of Patent: May 5, 1998
    Assignee: Craig Lesser
    Inventors: Craig Lesser, Reid W. Von Borstel
  • Patent number: D393375
    Type: Grant
    Filed: April 9, 1997
    Date of Patent: April 14, 1998
    Inventor: Rick C. Lee
  • Patent number: D401376
    Type: Grant
    Filed: February 6, 1998
    Date of Patent: November 17, 1998
    Assignee: Michigan Avenue Industrial Corporation
    Inventor: Yeou-Mine Ho