Abstract: Bioartificial implants and methods for their manufacture and use are described, particularly bioartificial pancreases. In particular, the implants may be thin sheets which enclose cells, may be completely biocompatible over extended periods of time and may not induce fibrosis. The high-density-cell-containing thin sheets are preferably completely retrievable, and have dimensions allowing maintenance of optimal tissue viability through rapid diffusion of nutrients and oxygen and also allowing rapid changes in the secretion rate of insulin and/or other bioactive agents in response to changing physiology. Implantations of living cells, tissue, drugs, medicines and/or enzymes, contained in the bioartificial implants may be made to treat and/or prevent disease.

Abstract: A process for decolorizing a cellulose textile bearing oxidized vat dye comprising contacting the cellulose textile with an aqueous solution of hydrogen peroxide containing an amount of a hydrogen peroxide catalyst sufficient to oxidize vat dye in the fabric until the dye is decolorized by oxidation. Then the cellulose textile is separated from the aqueous solution. The hydrogen peroxide catalyst can be a water-soluble lower alkyl quaternary amine salt such as a dihydroxypropyltrimethylammonium halide, chlorohydroxypropyltrimethylammonium halide or epoxypropyltrimethylammonium halide, or it can be a transition metal ion such as a cupric or stannous metal ion present in an amount of from 0.1 to 2 ppm. The process is suitable for decolorizing denim bearing vat dyes such as indigo, and is particularly suitable for decolorizing denim scrap.

Abstract: A method of coating a solid support (e.g. a capillary or chromatography packing) to alter the properties of the support surface for separating components in a fluid stream. The method comprises (a) covalently binding a coupling agent (including functional groups capable of forming free radical sites under hydrogen abstraction conditions) to the support surface in a uniform layer, and (b) thereafter, contacting the bound coupling agent with a solution of preformed polymer comprising totally saturated carbon chain backbones including leaving groups, under hydrogen abstraction conditions of elevated temperature in the presence of a free radical catalyst to remove leaving groups from the carbon chains to form free radical carbon binding sites which covalently bond to the coupling agent layer and to crosslink at least some of the preformed polymer through the free radical carbon binding sites to form a dimensional polymer network coating on said solid support surface.

Abstract: A method for sterilizing fresh produce (e.g. onions) comprising contacting the produce with an aqueous solution of an oxidizing agent (e.g. hydrogen peroxide) under a pressure of at least 25 psig for sufficient time to significantly reduce the microbiological count.

Abstract: Disclosed is a method and apparatus for electrolytically generating an acid or base eluent in an aqueous solution and for simultaneously suppressing conductivity of the eluent in an ion exchange bed after chromatographic separation in an ion chromatography system.

Abstract: In accordance with the present invention, an improved bifunctional cation-exchange composition has been formed which comprises synthetic resin support particles and both crown ether and non-crown ether functional groups attached thereto. The compositions of the present invention provide for novel, enhanced cation separation capabilities and, depending upon the type of functional groups employed, permit effective separation of cations which elute at approximately the same time off standard and commonly used cation-exchange columns. The presently described bifunctional cation-exchange compositions also permit the effective separation of one cation from a mixture comprising another cation that is present at a significantly greater concentration. Formed articles and methods employing the bifunctional cation-exchange composition are also provided.

Abstract: In accordance with the present invention, an improved anion-exchange chromatographic composition has been formed which comprises synthetic resin support particles and anion exchange compounds attached thereto, wherein the anion-exchange compounds comprise an internal reactive group, which may be an ester, ketone or amide group, and a terminal quaternary ammonium salt which functions as an anion-exchange site. The compositions of the present invention exhibit improved hydrolytic stability as compared to other known anion-exchange chromatographic compositions due to the presence of linkers which increase the number of atoms separating the internal reactive group from the nitrogen atom of the terminal ammonium anion-exchange site. Formed articles and methods employing the anion-exchange chromatographic composition are also provided.

Abstract: In accordance with the present invention, an improved anion- exchange chromatographic composition has been formed which comprises synthetic resin support particles and anion exchange compounds attached thereto, wherein the anion-exchange compounds comprise an internal reactive group, which may be an ester, ketone or amide group, and a terminal quaternary ammonium salt which functions as an anion-exchange site. The compositions of the present invention exhibit improved hydrolytic stability as compared to other known anion-exchange chromatographic compositions due to the presence of linkers which increase the number of atoms separating the internal reactive group from the nitrogen atom of the terminal ammonium anion-exchange site. Formed articles and methods employing the anion-exchange chromatographic composition are also provided.