Patents Represented by Attorney David J. Meyer
  • Patent number: 5298489
    Abstract: Human lipocortins III, IV, V and VI, DNA sequences and recombinant DNA molecules that are characterized in that they code for these human lipocortins. Hosts transformed with these sequences may be employed in the processes of this invention to produce the human lipocortin molecules of this invention. These polypeptides possess anti-inflammatory activity and are useful in the treatment of arthritic, allergic, dermatologic, ophthalmic and collagen diseases.
    Type: Grant
    Filed: March 13, 1991
    Date of Patent: March 29, 1994
    Assignee: Biogen, Inc.
    Inventors: Barbara P. Wallner, R. Blake Pepinsky, Jeffrey L. Browning
  • Patent number: 5162499
    Abstract: Synthetic linear or cyclic peptides having the formula[A].sub.x -[B].sub.x -Ser-Ser-Ser-Asn-Tyr-[C].sub.xwhereinA is L-Ala, DL-Ala, D-Ala, Gly, or Val;B is L-Ala, DL-Ala, D-Ala, Gly, or Val;C is L-Met, L-Met (O), Cys, Thr or Gly; andx is an integer of from 0-1.A method of treating AIDS by administering the synthetic peptides is also provided.
    Type: Grant
    Filed: November 19, 1991
    Date of Patent: November 10, 1992
    Assignee: Heterocyclic Research, Inc.
    Inventors: Miroslav Trampota, Matthew Pincus
  • Patent number: 4950646
    Abstract: DNA sequences, recombinant DNA molecules and hosts transformed with them which produce human lipocortin-like polypeptides and methods of making and using these products. The DNA sequences and recombinant DNA molecules are characterized in that they code on expression for a human lipocortin-like polypeptide. In appropriate hosts these DNA sequences permit the production of human lipocortin-like polypeptides useful as anti-inflammatory agents and methods in the treatment of arthritic, allergic, dermatologic, ophthalmic and collagen diseases as well as other disorders involving inflammatory processes.
    Type: Grant
    Filed: January 10, 1986
    Date of Patent: August 21, 1990
    Assignee: Biogen, Inc.
    Inventors: Barbara P. Wallner, R. Blake Pepinsky, Jeffrey L. Garwin, Daniel G. Schindler, Kuo-Sen Huang
  • Patent number: 4879224
    Abstract: DNA sequences, recombinant DNA molecules and hosts transformed with them which produce human phospholipase inhibitor polypeptides and methods of making and using these products. The DNA sequences and recombinant DNA molecules are characterized in that they code on expression for a human phospholipase inhibitor polypeptide. In appropiate hosts these DNA sequences permit the production of human phospholipase inhibitor polypeptides.
    Type: Grant
    Filed: January 10, 1985
    Date of Patent: November 7, 1989
    Assignee: Biogen, Inc.
    Inventors: Barbara P. Wallner, R. Blake Pepinsky, Jeffrey L. Garwin
  • Patent number: 4874743
    Abstract: DNA sequences, recombinant DNA molecules and hosts transformed with them which produce human phospholipase inhibitor-like polypeptides and methods of making and using these products. The DNA sequences and recombinant DNA molecules are characterized in that they code on expression for a human phospholipase inhibitor-like polypeptide. In appropriate hosts these DNA sequences permit the production of human phospholipase inhibitor-like polypeptides useful as anti-inflammatory agents and methods in the treatment of arthritic, allergic, dermatologic, ophthalmic and collagen diseases as well as other disorders involving inflammatory processes.
    Type: Grant
    Filed: March 15, 1985
    Date of Patent: October 17, 1989
    Assignee: Biogen, Inc.
    Inventors: Barbara P. Wallner, R. Blake Pepinsky, Jeffrey L. Garwin