Abstract: An opto-electronic device utilizes a band of partially polarized polychromatic light for quantitative analysis of a specimen containing a target molecule. The device comprises: a polarizer for producing a segmented band of partially polarized polychromatic light from the band of partially polarized polychromatic light; a specimen cell adapted for receiving the specimen and for transporting said segmented band of partially polarized polychromatic light to the specimen; a polarizing analyzer optically coupled to said segmented band of partially polarized polychromatic light exiting the specimen; and comparison means for comparing said segmented band of partially polarized polychromatic light before entering the specimen with said segmented band of partially polarized polychromatic light after exiting the specimen. The target molecule changes ellipticity of said segmented band of partially polarized polychromatic light and said polarizer is synchronized with said polarizing analyzer.