Patents Represented by Attorney David P. Ruschke

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  • Implantable medical device with controllable gaseous agent release system
    Patent number: 7122027
    Abstract: The present invention generally relates to medical devices. Specifically, the invention pertains to implantable medical devices that produces gaseous agents from precursors and releases them into the body. More specifically, the invention provides for the controlled release of the gaseous agent to the body to produce a local or systemic therapeutic effect.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: October 17, 2006
    Assignee: Medtronic, Inc.
    Inventors: Paul V. Trescony, Kenneth E. Rohly, James R. Keogh, Darrell F. Untereker, Naim S. Istephanous
  • Method for attachment of biomolecules to medical device surfaces
    Patent number: 7122356
    Abstract: A method for making a medical device having at least one biomolecule immobilized on a substrate surface is provided. One method of the present invention includes immobilizing a biomolecule comprising an unsubstituted amide moiety on a biomaterial surface. Another method of the present invention includes immobilizing a biomolecule on a biomaterial surface comprising an unsubstituted amide moiety. Still another method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties immobilized on medical device surfaces. Additionally, one method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties in solution, thereby forming a crosslinked biomaterial or a crosslinked medical device coating.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: October 17, 2006
    Assignee: Medtronic, Inc.
    Inventors: James R. Keogh, Paul V. Trescony
  • Heparin compositions and methods of making and using the same
    Patent number: 6953625
    Abstract: Heparin-polyoxyalkylenepolyamine adducts, and methods of making and using such adducts are disclosed. Compositions including a quaternary ammonium heparin complex, a moisture curable polysiloxane, and an organic solvent are also disclosed, along with methods of making and using such compositions.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: October 11, 2005
    Assignee: Medtronic, Inc.
    Inventor: Edouard Koulik
  • Polymeric materials with improved dielectric breakdown strength
    Patent number: 6879861
    Abstract: A novel polymeric electrically insulating material that includes a linked voltage stabilizing agent. Also provided are methods of making the novel material and articles and devices that incorporate the novel material, particularly implantable medical devices.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: April 12, 2005
    Assignee: Medtronic, Inc.
    Inventors: Michael E. Benz, Mark A. Tapsak, Angela Pratt, Randall V. Sparer
  • Degradable polymers from derivatized ring-opened epoxides
    Patent number: 6730772
    Abstract: A polymer of a ring-opened functionalized epoxide is formed by the polymerization of a functionalized epoxide monomer having the structure E-CHR-G wherein E represents an epoxide group, R is hydrogen or an alkyl group, and G is a derivatizable group such as an unsaturated functionality or ester substituent.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: May 4, 2004
    Inventor: Venkatram P. Shastri