Patents Represented by Attorney, Agent or Law Firm David Preston
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Patent number: 6834955Abstract: The present invention recognizes that lenses, such as contact lenses, can be pigmented using ink that include polymers or polymerizable monomers, preferably the same monomers used to make the lens. The ink can be used to make images on or within the lens. Images made using these inks are preferably digital and can be used in a variety of printing methods, including ink-jet printing.Type: GrantFiled: September 7, 2001Date of Patent: December 28, 2004Inventor: Praful Doshi
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Patent number: 6806050Abstract: This invention provides electromagnetic chips and electromagnetic biochips having arrays of individually addressable micro-electromagnetic units, as well as methods of utilizing these chips for directed manipulation of micro-particles and micro-structures such as biomolecules and chemical reagents. An electromagnetic biochip comprises an individually addressable micro-electromagnetic unit chip with ligand molecules immobilized on its surface. By controlling the electromagnetic field at each unit of the array and combining this control with magnetic modification of biomolecules, these chips can be used for directed manipulation, synthesis and release of biomolecules in order to increase sensitivity of biochemical or chemical analysis and reduce assay time. Other advantages with these chips include minimized damages to biological molecules and increased reproducibility of assay results.Type: GrantFiled: September 18, 2001Date of Patent: October 19, 2004Assignee: AVIVA BiosciencesInventors: Yuxiang Zhou, Litian Liu, Ken Chen, Depu Chen, Jia Wang, Zewen Liu, Zhimin Tan, Junquan Xu, Xiaoshan Zhu, Xuezhong He, Wenzhang Xie, Zhiming Li, Xiumel Liu
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Patent number: 6716642Abstract: The present invention provides electromagnetic chips and electromagnetic biochips having arrays of individually addressable micro-electromagnetic units, as well as methods of utilizing these chips for directed manipulation of micro-particles and micro-structures such as biomolecules and chemical reagents.Type: GrantFiled: October 10, 2000Date of Patent: April 6, 2004Assignee: Aviva Biosciences CorporationInventors: Lei Wu, Xiaobo Wang, Jing Cheng, Weiping Yang, YuXiang Zhou, LiTian Liu, Junquan Xu
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Patent number: 6706495Abstract: The present invention provides an isolated Staphylococcal GTPase obg gene and a Staphylococcal GTP-binding protein encoded thereby. A recombinant expression vector and an engineered host cell are also provided that include a polynucleotide encoding a Staphylococcal GTP-binding protein. The present invention further relates to a method of producing Staphylococcal GTP-binding protein and a method for high throughput screening to identify potential antimicrobial compounds useful against Staphylococcal bacterial strains.Type: GrantFiled: February 23, 2001Date of Patent: March 16, 2004Assignee: Anadys PharmaceuticalsInventors: Yueh-tyng Chien, Jason A. Thresher, C. Richard Wobbe, Judith M. Healy
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Patent number: 6623936Abstract: A method for diagnosing clinically distinct embryonal and alveolar subtypes of rhabdomyosarcoma, including contacting a reagent including an antibody that specifically binds myogenin with a sample that includes at least one rhabdomyosarcoma cell or at least one extract of at least one rhabdomyosarcoma cell, detecting the binding of the antibody to the sample to determine the presence, absence, or amount of myogenin in the sample, and diagnosing clinically distinct embryonal and alveolar subtypes of rhabdomyosarcoma, alveolar rhabdomyosarcoma having an increased amount of binding as compared to embryonal rhabdomyosarcoma.Type: GrantFiled: February 7, 2000Date of Patent: September 23, 2003Assignee: ImgenexInventors: Peter Dias, Sujay Singh
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Patent number: 6565808Abstract: The present invention recognizes that it can be desirable to have a sample receiving chamber integral to or engageable with a test platform, such as a test platform that includes a test strip. The sample receiving chamber is preferably separate or separable from the test platform, but that need not be the case. Preferably, a fluid flow actuating device or structure, such as a valve separates the sample receiving chamber from the test platform. A first aspect of the present invention is a test device that includes a sample receiving chamber and a test platform that preferably includes a test element. A second aspect of the present invention is a method of detecting an analyte in a sample, including: providing a sample, contacting the sample with a test device and detecting the analyte in the sample.Type: GrantFiled: May 18, 2001Date of Patent: May 20, 2003Assignee: Acon LaboratoriesInventors: Robert Thomas Hudak, Lorraine Bautista
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Patent number: 6451582Abstract: The present invention relates to a recombinant organism, and a bacterial strain such as Staphylococcus, and S. aureus, in particular. The organism has a regulatable gene for encoding an RNA polymerase specificity factor required for expression of at least one gene essential for growth of the organism. The regulatable gene is one which is responsive to an exogenous effector molecule, and may in particular be an inducer-responsive gene including an operator site, such as a lac operator, to which a repressor, such as a lacl-encoded repressor, is capable of binding. The regulatable gene may in particular be an IPTG responsive plaC allele.Type: GrantFiled: February 10, 2000Date of Patent: September 17, 2002Assignee: Anadys Pharmaceuticals, IncInventors: Judith M. Healy, C. Richard Wobbe, Patricia Carroll, Jason Thresher
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Patent number: 6355491Abstract: This invention provides electromagnetic chips and electromagnetic biochips having arrays of individually addressable micro-electromagnetic units, as well as methods of utilizing these chips for directed manipulation of micro-particles and micro-structures such as biomolecules and chemical reagents. An electromagnetic biochip comprises an individually addressable micro-electromagnetic unit chip with ligand molecules immobilized on its surface. By controlling the electromagnetic field at each unit of the array and combining this control with magnetic modification of biomolecules, these chips can be used for directed manipulation, synthesis and release of biomolecules in order to increase sensitivity of biochemical or chemical analysis and reduce assay time. Other advantages with these chips include minimized damages to biological molecules and increased reproducibility of assay results.Type: GrantFiled: September 17, 1999Date of Patent: March 12, 2002Assignee: Aviva BiosciencesInventors: Yuxiang Zhou, Litian Liu, Ken Chen, Depu Chen, Jia Wang, Zewen Liu, Zhimin Tan, Junquan Xu, Xiaoshan Zhu, Xuezhong He, Wenzhang Xie, Zhiming Li, Xiumei Liu
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Patent number: 6315410Abstract: The present invention recognizes that lenses, such as contact lenses, can be pigmented using ink that include polymers or polymerizable monomers, preferably the same monomers used to make the lens. The ink can be used to make images on or within the lens. Images made using these inks are preferably digital and can be used in a variety of printing methods, including ink-jet printing.Type: GrantFiled: October 25, 2000Date of Patent: November 13, 2001Inventor: Praful Doshi
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Patent number: D464141Type: GrantFiled: October 17, 2000Date of Patent: October 8, 2002Assignee: Acon Laboratories, Inc.Inventors: Jim McMenamy, James Feng Lin
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Patent number: D468437Type: GrantFiled: November 21, 2000Date of Patent: January 7, 2003Assignee: Acon Laboratories, Inc.Inventors: Jim McMenamy, James Feng Lin